Zebrafish syndromic albinism models as tools for understanding and treating pigment cell disease in humans

SJ Neuffer, CD Cooper - Cancers, 2022 - mdpi.com
Simple Summary Zebrafish (Danio rerio) is an emerging model for studying many diseases,
including disorders originating in black pigment cells, melanocytes. In this review of the …

An intronic transposon insertion associates with a trans-species color polymorphism in Midas cichlid fishes

CF Kratochwil, AF Kautt, A Nater, A Härer… - Nature …, 2022 - nature.com
Polymorphisms have fascinated biologists for a long time, but their genetic underpinnings
often remain elusive. Here, we aim to uncover the genetic basis of the gold/dark …

kcnj13 regulates pigment cell shapes in zebrafish and has diverged by cis-regulatory evolution between Danio species

M Podobnik, AP Singh, Z Fu, CM Dooley… - …, 2023 - journals.biologists.com
Teleost fish of the genus Danio are excellent models to study the genetic and cellular bases
of pigment pattern variation in vertebrates. The two sister species Danio rerio and Danio …

[HTML][HTML] Thyroid hormone regulates abrupt skin morphogenesis during zebrafish postembryonic development

AJ Aman, M Kim, LM Saunders, DM Parichy - Developmental biology, 2021 - Elsevier
Thyroid hormone is a key regulator of post-embryonic vertebrate development. Skin is a
biomedically important thyroid hormone target organ, but the cellular and molecular …

Pigment pattern morphospace of Danio fishes: evolutionary diversification and mutational effects

BM McCluskey, Y Liang, VM Lewis… - Biology …, 2021 - journals.biologists.com
Molecular and cellular mechanisms underlying variation in adult form remain largely
unknown. Adult pigment patterns of fishes in the genus Danio, which includes zebrafish …

Transcriptomic profiling of tissue environments critical for post-embryonic patterning and morphogenesis of zebrafish skin

AJ Aman, LM Saunders, AA Carr, S Srivatasan… - Elife, 2023 - elifesciences.org
Pigment patterns and skin appendages are prominent features of vertebrate skin. In
zebrafish, regularly patterned pigment stripes and an array of calcified scales form …

[HTML][HTML] Restraint of melanoma progression by cells in the local skin environment

Y Ma, M Tagore, MV Hunter, TH Huang, E Montal… - …, 2024 - pmc.ncbi.nlm.nih.gov
Keratinocytes, the dominant cell type in the melanoma microenvironment during tumor
initiation, exhibit diverse effects on melanoma progression. Using a zebrafish model of …

Cis-regulatory evolution of the potassium channel gene kcnj13 during pigment pattern diversification in Danio fish

M Podobnik, AP Singh, Z Fu, CM Dooley… - bioRxiv, 2022 - biorxiv.org
Teleost fish of the genus Danio are excellent models to study the genetic and cellular bases
of pigment pattern variation in vertebrates. The two sister species Danio rerio and Danio …

A zebrafish system for identifying genetic dependencies in melanocytes and melanoma

S Perlee, Y Ma, MV Hunter, JB Swanson, Z Ming, J Xia… - bioRxiv, 2024 - biorxiv.org
The advent of large-scale sequencing in both development and disease has identified large
numbers of candidate genes that may be linked to important phenotypes. Validating the …

[PDF][PDF] kcnj13 regulates pigment cell shapes in zebrafish and has diverged by cis-regulatory evolution between Danio species

M Firlej, SJ Stednitz, H Elhabashy, S Weyand10… - 2023 - researchgate.net
Teleost fish of the genus Danio are excellent models to study the genetic and cellular bases
of pigment pattern variation in vertebrates. The two sister species Danio rerio and Danio …