[HTML][HTML] RNA nanotechnology-mediated cancer immunotherapy

YX Lin, Y Wang, S Blake, M Yu, L Mei, H Wang… - Theranostics, 2020 - ncbi.nlm.nih.gov
RNA molecules (eg, siRNA, microRNA, and mRNA) have shown tremendous potential for
immunomodulation and cancer immunotherapy. They can activate both innate and adaptive …

Preclinical and clinical evidence of immune responses triggered in oncologic photodynamic therapy: clinical recommendations

I Beltrán Hernández, Y Yu, F Ossendorp… - Journal of clinical …, 2020 - mdpi.com
Photodynamic therapy (PDT) is an anticancer strategy utilizing light-mediated activation of a
photosensitizer (PS) which has accumulated in tumor and/or surrounding vasculature. Upon …

[HTML][HTML] Booster doses of COVID-19 vaccines for patients with haematological and solid cancer: a systematic review and individual patient data meta-analysis

AS Mai, ARYB Lee, RYK Tay, L Shapiro… - European Journal of …, 2022 - Elsevier
Importance Patients with cancer have an increased risk of severe disease and mortality from
COVID-19, as the disease and antineoplastic therapy cause reduced vaccine …

TNF-α-induced Tim-3 expression marks the dysfunction of infiltrating natural killer cells in human esophageal cancer

Y Zheng, Y Li, J Lian, H Yang, F Li, S Zhao, Y Qi… - Journal of translational …, 2019 - Springer
Background Impairment of natural killer (NK) cell activity is an important mechanism of tumor
immunoevasion. T cell immunoglobulin domain and mucin domain-3 (Tim-3) is an activation …

NF-κB pathways are involved in M1 polarization of RAW 264.7 macrophage by polyporus polysaccharide in the tumor microenvironment

CP Liu, X Zhang, QL Tan, WX Xu, CY Zhou, M Luo… - PloS one, 2017 - journals.plos.org
Bladder cancer is one of the most malignant tumors closely associated with macrophages.
Polyporus polysaccharide (PPS) has shown excellent efficacy in treating bladder cancer …

[HTML][HTML] Impact of COVID-19 vaccination on the use of PD-1 inhibitor in treating patients with cancer: a real-world study

Q Mei, G Hu, Y Yang, B Liu, J Yin, M Li… - … for immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Anti-COVID-19 vaccination may have functional implications for immune checkpoint inhibitor
treatment in patients with cancer. This study was undertaken to determine whether the safety …

Natural killer cells and T cells in hepatocellular carcinoma and viral hepatitis: current status and perspectives for future immunotherapeutic approaches

SG Kalathil, Y Thanavala - Cells, 2021 - mdpi.com
Natural killer (NK) cells account for 25–50% of the total number of hepatic lymphocytes,
which implicates that NK cells play an important role in liver immunity. The frequencies of …

[HTML][HTML] Heme oxygenase-1 orchestrates the immunosuppressive program of tumor-associated macrophages

E Alaluf, B Vokaer, A Detavernier, A Azouz… - Jci Insight, 2020 - ncbi.nlm.nih.gov
Tumor-associated macrophages (TAMs) contribute to the maintenance of a strong
immunosuppressive environment, supporting tumor progression and resistance to treatment …

[HTML][HTML] Augmentation of IFN-γ+ CD8+ T cell responses correlates with survival of HCC patients on sorafenib therapy

SG Kalathil, A Hutson, J Barbi, R Iyer, Y Thanavala - JCI insight, 2019 - ncbi.nlm.nih.gov
BACKGROUND Sorafenib has been shown to reduce the extent of immunosuppression in
patients with hepatocellular carcinoma (HCC). The rationale of this investigation was to …

[HTML][HTML] Cancer is associated with severe disease in COVID-19 patients: a systematic review and meta-analysis

R Ofori-Asenso, O Ogundipe, AA Agyeman… - …, 2020 - ncbi.nlm.nih.gov
Cancer patients are vulnerable to complications of respiratory viruses. This systematic
review and meta-analysis sought to examine the prevalence of cancer and its association …