Insects comprise the largest species composition in the entire animal kingdom and possess
a vast undiscovered genetic diversity and gene pool that can be better explored using …

Over the past 30 years, the characteristics that have made the nematode Caenorhabditis
elegans one of the premier animal model systems have also allowed it to emerge as a …

Recombinant-inbred populations, generated from a cross between Caenorhabditis elegans
strains Bergerac-BO and RC301, were used to identify quantitative trait loci (QTL) affecting …

Background PRISE2 is a new software tool for designing sequence-selective PCR primers
and probes. To achieve high level of selectivity, PRISE2 allows the user to specify a …

Quantitative trait loci (QTL) can implicate an unbiased sampling of genes underlying a
complex, polygenic phenotype. QTL affecting longevity in Caenorhabditis elegans were …

This report presents PRImer Selector (PRISE), a new software package that implements
several features that improve and streamline the design of sequence-selective PCR primers …

Quantitative trait locus (QTL) mapping provides a means to discover and roughly position
regions of the genome that harbor genes responsible for natural variation in a complex trait …

By linkage mapping of quantitative trait loci, we previously identified at least 11 natural
genetic variants that significantly modulate Caenorhabditis elegans life-span (LS), many of …

Figure 1. Transposon insertion display (TID) strategies. Transposon (black), genomic
(white), and adaptor sequences (gray and hatched boxes) are represented. Genomic DNA is …

Lamins are components of the nuclear lamina and are divided In A and B-types, which
Interact with proteins of the inner nuclear membrane like emerin. Mutations in emerin (X …