Over the past 30 years, the characteristics that have made the nematode Caenorhabditis elegans one of the premier animal model systems have also allowed it to emerge as a …
Recombinant-inbred populations, generated from a cross between Caenorhabditis elegans strains Bergerac-BO and RC301, were used to identify quantitative trait loci (QTL) affecting …
Background PRISE2 is a new software tool for designing sequence-selective PCR primers and probes. To achieve high level of selectivity, PRISE2 allows the user to specify a …
S Ayyadevara, R Ayyadevara, A Vertino, A Galecki… - Genetics, 2003 - academic.oup.com
Quantitative trait loci (QTL) can implicate an unbiased sampling of genes underlying a complex, polygenic phenotype. QTL affecting longevity in Caenorhabditis elegans were …
Q Fu, P Ruegger, E Bent, M Chrobak… - Journal of microbiological …, 2008 - Elsevier
This report presents PRImer Selector (PRISE), a new software package that implements several features that improve and streamline the design of sequence-selective PCR primers …
Quantitative trait locus (QTL) mapping provides a means to discover and roughly position regions of the genome that harbor genes responsible for natural variation in a complex trait …
By linkage mapping of quantitative trait loci, we previously identified at least 11 natural genetic variants that significantly modulate Caenorhabditis elegans life-span (LS), many of …
QH Le, T Bureau - Biotechniques, 2004 - Taylor & Francis
Figure 1. Transposon insertion display (TID) strategies. Transposon (black), genomic (white), and adaptor sequences (gray and hatched boxes) are represented. Genomic DNA is …
Lamins are components of the nuclear lamina and are divided In A and B-types, which Interact with proteins of the inner nuclear membrane like emerin. Mutations in emerin (X …