Photochemical release (uncaging) of small molecule bioregulators (SMBs) such as nitric
oxide (NO) or carbon monoxide (CO) at physiological sites offers exquisite control of timing …

Background and purpose Since 2001, symptom cluster research has grown considerably.
However, because multiple methodological considerations remain, ongoing synthesis of the …

Purpose Sleep disturbance and cancer-related fatigue (CRF) are among the most commonly
reported symptoms associated with breast cancer and its treatment. This study identified …

Objectives Neoadjuvant chemotherapy causes distressing symptoms, which have to be
managed by patients at home. Assessing and acting upon relevant patient-reported …

Context Pain, fatigue, sleep disturbance, and depression often co-occur in oncology patients
and negatively impact quality of life (QOL). Objectives Study purposes were to identify …

PURPOSE To identify symptom clusters among adult survivors of childhood cancers and test
associations with health-related quality of life (HRQOL) and physical and neurocognitive …

Context Cancer patients experience a broad range of physical and psychological symptoms
as a result of their disease and its treatment. On average, these patients report 10 unrelieved …

Objectives To consider future directions for symptom cluster research. These considerations
are organized using the two main conceptual approaches for symptom cluster research …

Chimeric antigen receptor T-cell therapy (CAR-T) has transformed the treatment for
relapsed/refractory hematologic malignancies; however, data on patient-reported outcomes …

Context Patients with breast cancer who undergo chemotherapy (CTX) experience between
10 and 32 concurrent symptoms. An evaluation of how these symptoms cluster together and …