Natural product research aims to characterize specialized metabolites from various living
organisms and assess their biological properties from either a chemical ecology or drug …

Covering: 2013 to 2019 The exploration of the chemical diversity of extracts from various
biological sources has led to major drug discoveries. Over the past two decades, despite the …

Electrospray ionization (ESI) operating in the negative mode coupled to high-resolution
mass spectrometry is the most popular technique for the characterization of dissolved …

Accurate quantification of polymer distributions is one of the main challenges in polymer
analysis by liquid chromatography. The response of contemporary detectors is typically …

Aerosol-based detectors developed within the last few decades have increasingly
addressed the need for sensitive, universal liquid chromatography detection in a wide …

Food and feed laboratories share several similarities when facing the implementation of
liquid-chromatographic analysis. Using the experience acquired over the years, through …

Polysialic acid (polySia) is a highly regulated polymer of sialic acid (Sia) with such potent
biophysical characteristics that when expressed drastically influences the interaction …

Psoraleae Fructus is one of the most popular traditional Chinese medicines. Coumarins,
flavonoids, and meroterpenes are the main contributors to the biological activity of …

The impurity profile of amino acids depends strongly on the production process. Since there
are many different production methods (eg fermentation, protein hydrolysis or chemical …

The charged aerosol detector (CAD) is the latest representative of aerosol-based detectors
that generate a response independent of the analytes' chemical structure. This study was …