Novel trends in hydrogel development for biomedical applications: A review

P Sánchez-Cid, M Jiménez-Rosado, A Romero… - Polymers, 2022 - mdpi.com
Nowadays, there are still numerous challenges for well-known biomedical applications,
such as tissue engineering (TE), wound healing and controlled drug delivery, which must be …

Advanced biomaterials for regulating polarization of macrophages in wound healing

J Mao, L Chen, Z Cai, S Qian, Z Liu… - Advanced Functional …, 2022 - Wiley Online Library
Macrophage immunotherapy is an emerging treatment strategy that modulates the immune
system to promote wound healing. The functionality and regeneration of tissue depend on …

Artificial nonenzymatic antioxidant MXene nanosheet-anchored injectable hydrogel as a mild photothermal-controlled oxygen release platform for diabetic wound …

Y Li, R Fu, Z Duan, C Zhu, D Fan - Acs Nano, 2022 - ACS Publications
Hypoxia, excessive reactive oxygen species (ROS), impaired angiogenesis, lasting
inflammation, and bacterial infection, are key problems impeding diabetic wound healing …

Rapid self-healing and self-adhesive chitosan-based hydrogels by host-guest interaction and dynamic covalent bond as flexible sensor

Z Ren, T Ke, Q Ling, L Zhao, H Gu - Carbohydrate Polymers, 2021 - Elsevier
A sensor used to monitor tissue deformation requires good flexibility, stretchability, self-
adhesion, cyto-compatibility, and antibacterial property. Here, we prepared hydrogel sensor …

Multifunctional hydrogels for the healing of diabetic wounds

T Xiang, Q Guo, L Jia, T Yin, W Huang… - Advanced …, 2024 - Wiley Online Library
The healing of diabetic wounds is hindered by various factors, including bacterial infection,
macrophage dysfunction, excess proinflammatory cytokines, high levels of reactive oxygen …

Advances in modified hyaluronic acid-based hydrogels for skin wound healing

YW Ding, ZY Wang, ZW Ren, XW Zhang… - Biomaterials Science, 2022 - pubs.rsc.org
Hyaluronic acid (HA) is a natural linear anionic polysaccharide with many unique
characteristics such as excellent biocompatibility and biodegradability, native …

Polysaccharide-based multifunctional hydrogel bio-adhesives for wound healing: A review

J Yang, S Wang - Gels, 2023 - mdpi.com
Wound healing is a long-term and complex biological process that involves multiple
hemostasis, inflammation, proliferation, and remodeling stages. In order to realize …

Immunomodulatory hydrogels: advanced regenerative tools for diabetic foot ulcer

Y Xiong, Q Feng, L Lu, K Zha, T Yu, Z Lin… - Advanced Functional …, 2023 - Wiley Online Library
Diabetic foot ulcer (DFU) is one of the most common complications of diabetes, bringing
physical and mental challenges for patients due to the lack of efficient curative therapy …

[HTML][HTML] Modulating the immune system towards a functional chronic wound healing: A biomaterials and Nanomedicine perspective

K Las Heras, I Garcia-Orue, F Rancan, M Igartua… - Advanced Drug Delivery …, 2024 - Elsevier
Chronic non-healing wounds persist as a substantial burden for healthcare systems,
influenced by factors such as aging, diabetes, and obesity. In contrast to the traditionally pro …

Designing hydrogels for immunomodulation in cancer therapy and regenerative medicine

Z Zhang, C He, X Chen - Advanced Materials, 2024 - Wiley Online Library
The immune system not only acts as a defense against pathogen and cancer cells, but also
plays an important role in homeostasis and tissue regeneration. Targeting immune systems …