Phylogenetic and phylodynamic approaches to understanding and combating the early SARS-CoV-2 pandemic

SW Attwood, SC Hill, DM Aanensen… - Nature Reviews …, 2022 - nature.com
Determining the transmissibility, prevalence and patterns of movement of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infections is central to our understanding …

[HTML][HTML] Omicron variant (B. 1.1. 529) and its sublineages: What do we know so far amid the emergence of recombinant variants of SARS-CoV-2?

M Dhawan, ARA Saied, S Mitra, FA Alhumaydhi… - Biomedicine & …, 2022 - Elsevier
Since the start of the COVID-19 pandemic, numerous variants of SARS-CoV-2 have been
reported worldwide. The advent of variants of concern (VOCs) raises severe concerns amid …

Global landscape of SARS-CoV-2 genomic surveillance and data sharing

Z Chen, AS Azman, X Chen, J Zou, Y Tian, R Sun… - Nature …, 2022 - nature.com
Genomic surveillance has shaped our understanding of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) variants. We performed a global landscape analysis on SARS …

Outbreak. info genomic reports: scalable and dynamic surveillance of SARS-CoV-2 variants and mutations

K Gangavarapu, AA Latif, JL Mullen, M Alkuzweny… - Nature …, 2023 - nature.com
In response to the emergence of SARS-CoV-2 variants of concern, the global scientific
community, through unprecedented effort, has sequenced and shared over 11 million …

Pandemic-scale phylogenomics reveals the SARS-CoV-2 recombination landscape

Y Turakhia, B Thornlow, A Hinrichs, J McBroome… - Nature, 2022 - nature.com
Accurate and timely detection of recombinant lineages is crucial for interpreting genetic
variation, reconstructing epidemic spread, identifying selection and variants of interest, and …

Unlocking capacities of genomics for the COVID-19 response and future pandemics

S Knyazev, K Chhugani, V Sarwal, R Ayyala, H Singh… - Nature …, 2022 - nature.com
During the COVID-19 pandemic, genomics and bioinformatics have emerged as essential
public health tools. The genomic data acquired using these methods have supported the …

[PDF][PDF] Mutation rates and selection on synonymous mutations in SARS-CoV-2

N De Maio, CR Walker, Y Turakhia… - Genome biology and …, 2021 - academic.oup.com
The COVID-19 pandemic has seen an unprecedented response from the sequencing
community. Leveraging the sequence data from more than 140,000 SARS-CoV-2 genomes …

Detection and characterization of the SARS-CoV-2 lineage B. 1.526 in New York

AP West Jr, JO Wertheim, JC Wang… - Nature …, 2021 - nature.com
Abstract Wide-scale SARS-CoV-2 genome sequencing is critical to tracking viral evolution
during the ongoing pandemic. We develop the software tool, Variant Database (VDB), for …

Inference of phylogenetic trees directly from raw sequencing reads using Read2Tree

D Dylus, A Altenhoff, S Majidian, FJ Sedlazeck… - Nature …, 2024 - nature.com
Current methods for inference of phylogenetic trees require running complex pipelines at
substantial computational and labor costs, with additional constraints in sequencing …

A daily-updated database and tools for comprehensive SARS-CoV-2 mutation-annotated trees

J McBroome, B Thornlow, AS Hinrichs… - Molecular biology …, 2021 - academic.oup.com
The vast scale of SARS-CoV-2 sequencing data has made it increasingly challenging to
comprehensively analyze all available data using existing tools and file formats. To address …