Base‐modified fluorescent nucleoside analog probes have been very valuable in the study
of nucleic acid structure and function. Many of them structurally resemble natural bases, and …

Hybrid synthetic amphiphilic biomolecules are emerging as promising supramolecular
materials for biomedical and technological applications. Herein, recent progress in the field …

DNA polymerases can process a wide variety of structurally diverse nucleotide substrates,
but the molecular basis by which the analogs are processed is not completely understood …

Methods for tracking RNA inside living cells without perturbing their natural interactions and
functions are critical within biology and, in particular, to facilitate studies of therapeutic RNA …

Cellular RNA labeling strategies based on bioorthogonal chemical reactions are much less
developed in comparison to glycan, protein and DNA due to its inherent instability and lack …

A nucleoside bearing a solvatochromic push–pull fluorene fluorophore (dCFL) was
designed and synthesized by the Sonogashira coupling of alkyne-linked fluorene 8 with 5 …

Abstract Development of probes that can discriminate G-quadruplex (GQ) structures and
indentify efficient GQ binders on the basis of topology and nucleic acid type is highly desired …

Pd-catalyzed CC bond formation, an important vertebra in the spine of synthetic chemistry, is
emerging as a valuable chemoselective transformation for post-synthetic functionalization of …

We synthesized a small library of eighteen 5-substituted pyrimidine or 7-substituted 7-
deazapurine nucleoside triphosphates bearing methyl, ethynyl, phenyl, benzofuryl or …

A new fluorescent cytosine analog “tsC” containing a trans-stilbene moiety was synthesized
and incorporated into hemiprotonated base pairs that comprise i-motif structures. Unlike …