Smokeless tobacco and cigarette smoking: chemical mechanisms and cancer prevention
SS Hecht, DK Hatsukami - Nature Reviews Cancer, 2022 - nature.com
Tobacco products present a deadly combination of nicotine addiction and carcinogen
exposure resulting in millions of cancer deaths per year worldwide. A plethora of smokeless …
exposure resulting in millions of cancer deaths per year worldwide. A plethora of smokeless …
Biochemistry of nicotine metabolism and its relevance to lung cancer
SE Murphy - Journal of Biological Chemistry, 2021 - ASBMB
Nicotine is the key addictive constituent of tobacco. It is not a carcinogen, but it drives
smoking and the continued exposure to the many carcinogens present in tobacco. The …
smoking and the continued exposure to the many carcinogens present in tobacco. The …
Syndrome of combined pulmonary fibrosis and emphysema: an official ATS/ERS/JRS/ALAT research statement
Background: The presence of emphysema is relatively common in patients with fibrotic
interstitial lung disease. This has been designated combined pulmonary fibrosis and …
interstitial lung disease. This has been designated combined pulmonary fibrosis and …
Risk model–based lung cancer screening and racial and ethnic disparities in the US
Importance The revised 2021 US Preventive Services Task Force (USPSTF) guidelines for
lung cancer screening have been shown to reduce disparities in screening eligibility and …
lung cancer screening have been shown to reduce disparities in screening eligibility and …
Methods for using race and ethnicity in prediction models for lung cancer screening eligibility
Importance Using race and ethnicity in clinical prediction models can reduce or inadvertently
increase racial and ethnic disparities in medical decisions. Objective To compare eligibility …
increase racial and ethnic disparities in medical decisions. Objective To compare eligibility …
Racial/ethnic differences in lung cancer incidence in the multiethnic cohort study: an update
Background We previously found that African Americans and Native Hawaiians were at
highest lung cancer risk compared with Japanese Americans and Latinos; whites were …
highest lung cancer risk compared with Japanese Americans and Latinos; whites were …
[HTML][HTML] Electronic cigarette use and its association with asthma, chronic obstructive pulmonary disease (COPD) and asthma-COPD overlap syndrome among never …
METHODS Cross-sectional data from the Behavioral Risk Factor Surveillance System
(BRFSS) from 2016 to 2018 were used to examine self-reported information on current e …
(BRFSS) from 2016 to 2018 were used to examine self-reported information on current e …
Cancer in Africa: is it a genetic or environmental health problem?
Patients of African ancestry have the poorest outcome and the shortest survival rates from
cancer globally. This could be attributed to many variables including racial, biological …
cancer globally. This could be attributed to many variables including racial, biological …
LKB1 phosphorylation and deactivation in lung cancer by NNAL, a metabolite of tobacco-specific carcinogen, in an isomer-dependent manner
LKB1 loss of function is one key oncogenic event in lung cancer. Clinical data suggest that
LKB1 loss of function is associated with patients' smoking status. The responsible …
LKB1 loss of function is associated with patients' smoking status. The responsible …
Quantitative Liquid Chromatography–Nanoelectrospray Ionization–High-Resolution Tandem Mass Spectrometry Analysis of Acrolein-DNA Adducts and Etheno-DNA …
V Paiano, L Maertens, V Guidolin, J Yang… - Chemical research in …, 2020 - ACS Publications
Cigarette smoking is an important source of human exposure to toxicants and carcinogens
and contributes significantly to cancer morbidity and mortality worldwide. Acrolein, a …
and contributes significantly to cancer morbidity and mortality worldwide. Acrolein, a …