[HTML][HTML] Nanopore sequencing technology, bioinformatics and applications

Y Wang, Y Zhao, A Bollas, Y Wang, KF Au - Nature biotechnology, 2021 - nature.com
Rapid advances in nanopore technologies for sequencing single long DNA and RNA
molecules have led to substantial improvements in accuracy, read length and throughput …

[HTML][HTML] Phylogenetic analysis of transmission dynamics of dengue in large and small population centers, Northern Ecuador

S Márquez, G Lee, B Gutiérrez, S Bennett… - Emerging Infectious …, 2023 - ncbi.nlm.nih.gov
Although dengue is typically considered an urban disease, rural communities are also at
high risk. To clarify dynamics of dengue virus (DENV) transmission in settings with …

Lying in wait: the resurgence of dengue virus after the Zika epidemic in Brazil

AF Brito, LC Machado, RJ Oidtman… - Nature …, 2021 - nature.com
After the Zika virus (ZIKV) epidemic in the Americas in 2016, both Zika and dengue
incidence declined to record lows in many countries in 2017–2018, but in 2019 dengue …

Field and classroom initiatives for portable sequence-based monitoring of dengue virus in Brazil

TÉR Adelino, M Giovanetti, V Fonseca, J Xavier… - Nature …, 2021 - nature.com
Brazil experienced a large dengue virus (DENV) epidemic in 2019, highlighting a
continuous struggle with effective control and public health preparedness. Using Oxford …

[HTML][HTML] Rapid viral metagenomics using SMART-9N amplification and nanopore sequencing

IM Claro, MS Ramundo, TM Coletti… - Wellcome open …, 2021 - ncbi.nlm.nih.gov
Emerging and re-emerging viruses are a global health concern. Genome sequencing as an
approach for monitoring circulating viruses is currently hampered by complex and expensive …

Phylogenetics, epidemiology and temporal patterns of dengue virus in araraquara, são paulo state

CS de Souza, GS Caleiro, IM Claro, JG de Jesus… - Viruses, 2024 - mdpi.com
Dengue virus (DENV) is a prominent arbovirus with global spread, causing approximately
390 million infections each year. In Brazil, yearly epidemics follow a well-documented …

Phylogenetic Reconstructions Reveal the Circulation of a Novel Dengue Virus-1V Clade and the Persistence of a Dengue Virus-2 III Genotype in Northeast Brazil

H Fritsch, K Moreno, IAB Lima, CS Santos, BGG Costa… - Viruses, 2023 - mdpi.com
Dengue fever is among the most significant public health concerns in Brazil. To date, the
highest number of Dengue notifications in the Americas has been reported in Brazil, with …

Viral metagenomics for the identification of emerging infections in clinical samples with inconclusive Dengue, Zika, and Chikungunya viral amplification

JVC Souza, HO Santos, AB Leite, M Giovanetti… - Viruses, 2022 - mdpi.com
Viral metagenomics is increasingly being used for the identification of emerging and re-
emerging viral pathogens in clinical samples with unknown etiology. The objective of this …

Nanopore-based metagenomic sequencing in respiratory tract infection: a developing diagnostic platform

R Chapman, L Jones, A D'Angelo, A Suliman, M Anwar… - Lung, 2023 - Springer
Respiratory tract infection (RTI) remains a significant cause of morbidity and mortality across
the globe. The optimal management of RTI relies upon timely pathogen identification via …

Genetic differences of dengue virus 2 in patients with distinct clinical outcome

B de Carvalho Marques, L Sacchetto, CA Banho… - Brazilian Journal of …, 2023 - Springer
The genetic diversity of the dengue virus is characterized by four circulating serotypes,
several genotypes, and an increasing number of existing lineages that may have differences …