The nicotinamide/streptozotocin rodent model of type 2 diabetes: Renal pathophysiology and redox imbalance features

LJ Yan - Biomolecules, 2022 - mdpi.com
Diabetic nephropathy (DN) is a common complication of diabetes mellitus. While there has
been a great advance in our understanding of the pathogenesis of DN, no effective …

[HTML][HTML] S-Allyl-L-Cysteine—A garlic bioactive: Physicochemical nature, mechanism, pharmacokinetics, and health promoting activities

N Rais, A Ved, R Ahmad, M Kumar, MD Barbhai… - Journal of Functional …, 2023 - Elsevier
Abstract S-allyl-L-cysteine (SAC) is a sulfur-containing substance found in aged garlic
extract (AGE), which has been observed to have numerous biological activities, including …

Icariin ameliorates streptozocin-induced diabetic nephropathy through suppressing the TLR4/NF-κB signal pathway

M Qi, Y He, Y Cheng, Q Fang, R Ma, S Zhou, J Hao - Food & function, 2021 - pubs.rsc.org
Diabetic nephropathy (DN) is one of the complex and severe complications of diabetes
mellitus (DM). Icariin (ICA) is a flavonoid extracted from the leaves and stems of Herba …

[PDF][PDF] RETRACTED ARTICLE: Apigenin-Loaded Solid Lipid Nanoparticle Attenuates Diabetic Nephropathy Induced by Streptozotocin Nicotinamide Through Nrf2/HO …

P Li, SNA Bukhari, T Khan, R Chitti… - International journal …, 2020 - Taylor & Francis
Li P, Bukhari SNA, Khan T, et al. Int J Nanomedicine. 2020; 15: 9115–9124. The Editor and
Publisher of International Journal of Nanomedicine wish to retract the published article …

Pathophysiology of obesity-related infertility and its prevention and treatment by potential phytotherapeutics

VVS Uddandrao, P Brahma Naidu… - International Journal of …, 2024 - nature.com
Background Obesity is a complex multifactorial disease in which the accumulation of excess
body fat has adverse health effects, as it can increase the risk of several problems, including …

Circulating expression level of LncRNA Malat1 in diabetic kidney disease patients and its clinical significance

L Zhou, D Yang, LN Ou, XR Guo… - Journal of diabetes …, 2020 - Wiley Online Library
Background. Long noncoding RNA MALAT1 is closely related to diabetes and kidney
diseases and is expected to be a new target for the diagnosis and treatment of diabetic …

The potential therapeutic effects of Trifolium alexandrinum extract, hesperetin and quercetin against diabetic nephropathy via attenuation of oxidative stress …

HM Abdou, HTAE Abd Elkader - Chemico-Biological Interactions, 2022 - Elsevier
Diabetic nephropathy (DN) is one of the manifestations of systemic microangiopathy in
diabetes. Trifolium alexandrinum extract (TAE) contains biologically active phenolic …

Polyherbal formulation ameliorates diabetic cardiomyopathy through attenuation of cardiac inflammation and oxidative stress via NF-κB/Nrf-2/HO-1 pathway in …

VVS Uddandrao, B Parim, S Singaravel… - Journal of …, 2022 - journals.lww.com
The present study was intended to evaluate the effect of polyherbal formulation (PHF) made
with 3 nutraceuticals, such as Piper nigrum, Terminalia paniculata, and Bauhinia purpurea …

Grape seed proanthocyanidins protect pancreatic β cells against ferroptosis via the Nrf2 pathway in type 2 diabetes

H Li, H Zhang, T Wang, L Zhang, H Wang, H Lu… - … Trace Element Research, 2024 - Springer
Pancreatic β cell damage is the primary contributor to type 2 diabetes mellitus (T2DM);
however, the underlying mechanism remains nebulous. This study explored the role of …

Therapeutic role of Azadirachta indica leaves ethanolic extract against diabetic nephropathy in rats neonatally induced by streptozotocin

AEFBM El-Beltagy, AMB Saleh, A Attaallah… - Ultrastructural …, 2021 - Taylor & Francis
Diabetic nephropathy (DN) is manifested by chronic loss of renal function due to damage of
glomeruli and renal tubules. Therefore, this study is mainly designed to evaluate the …