Bacteria, similar to most organisms, have a love–hate relationship with metals: a specific
metal may be essential for survival yet toxic in certain forms and concentrations. Metal ions …

The clinical success of platinum-based chemotherapeutic agents was of enormous impact
on the discovery of novel metal N-heterocyclic carbene (NHC) complexes as potential anti …

There is a dire need for new antimicrobial compounds to combat the growing threat of
widespread antibiotic resistance. With a currently very scarce drug pipeline, consisting …

Silver coordination compounds with a number of different ligands (N-heterocyclic carbenes,
phosphines, N-heterocycles and others) possess several properties, ranging from …

Metal complexes in cancer therapy have attracted much interest mainly because metals
exhibit unique characteristics, such as redox activity, metal‐ligand interaction, structure and …

Because of their great structural diversity and multitude of chemical properties, N-
heterocyclic carbenes (NHCs) have been utilized in a variety of capacities. Most recently …

Treatment of triple-negative breast cancer (TNBC) has long been a medical challenge
because of the lack of effective therapeutic targets. Targeting lipid, carbohydrate, and …

Metal complexes gained more attention in the medical field, particularly cancer treatment,
due to their enhanced potential and redox ability. These complexes exhibited more …

The first synthesis of Pd–PEPPSI N-heterocyclic carbene complexes derived from the
abundant and renewable natural product caffeine is reported. The catalysts bearing 3-chloro …

New weapons are constantly needed in the fight against cancer. The discovery of cisplatin
as an anticancer drug prompted the search for new metal complexes. The successful history …