Glycosylation is catalyzed by various glycosyltransferase enzymes which are mostly located
in the Golgi apparatus in cells. These enzymes glycosylate various complex carbohydrates …

The majority of natural proteins contain (oligo)-saccharide side chains and therefore are
called glycoproteins. The saccharide residues are covalently linked to the protein backbone …

The ability to perform a dynamic kinetic asymmetric transformation (DYKAT) using the
palladium-catalyzed asymmetric allylic alkylation (AAA) is explored in the context of …

With nitrogen too: The first catalytic [3+ 2] annulation of aminocyclopropanes with enol
ethers is reported (see scheme; Phth= phthaloyl). The reaction worked with easily …

Abstract 3, 4, 6-Tri-O-acetyl-2-deoxy-2-trichloroacetamido-α-d-glucopyranosyl
trichloroacetimidate and its O-benzylated analogue were tested as glycosyl donors in the …

d-Glucosamine can be readily transformed into 1, 3, 4, 6-tetra-O-acetyl-2-deoxy-2-(2, 2, 2-
trichloroethoxycarbonylamino)-d-glucopyranose (2). From this intermediate valuable …

The iridium-catalyzed asymmetric allylic substitution is extended towards new
prenucleophiles like o-nosylamide, phthalimide as well as similar N, N-diacylamines (II) …

Novel bacterial topoisomerase inhibitors (NBTIs) are among the most promising new
antibiotics in preclinical/clinical development. We previously reported dioxane-linked NBTIs …

Mycobacterial arabinan is a common constituent of both arabinogalactan (AG) and
lipoarabinomannan (LAM). In this study, synthesis of β-Ara f containing common arabinan …

TMG-chitotriomycin, a potent and selective inhibitor of the β-N-acetylglucosaminidases that
possesses an unique N, N, N-trimethyl-d-glucosamine (TMG) residue, is revised to be the …