Exosomes as mediators of intercellular crosstalk in metabolism

R Isaac, FCG Reis, W Ying, JM Olefsky - Cell metabolism, 2021 - cell.com
Exosomes are nanoparticles secreted by all cell types and are a large component of the
broader class of nanoparticles termed extracellular vesicles (EVs). Once secreted …

[HTML][HTML] Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases

AL Cardoso, A Fernandes, JA Aguilar-Pimentel… - Ageing research …, 2018 - Elsevier
Objective Use of the frailty index to measure an accumulation of deficits has been proven a
valuable method for identifying elderly people at risk for increased vulnerability, disease …

Characterisation of adipocyte-derived extracellular vesicle subtypes identifies distinct protein and lipid signatures for large and small extracellular vesicles

M Durcin, A Fleury, E Taillebois, G Hilairet… - Journal of …, 2017 - Taylor & Francis
Extracellular vesicles (EVs) are biological vectors that can modulate the metabolism of target
cells by conveying signalling proteins and genomic material. The level of EVs in plasma is …

Depleting extracellular vesicles from fetal bovine serum alters proliferation and differentiation of skeletal muscle cells in vitro

H Aswad, A Jalabert, S Rome - BMC biotechnology, 2016 - Springer
Background Fetal bovine serum (FBS) contains a wide range of growth factors, hormones,
vitamins, amino acids, fatty acids and trace elements required for cell growth. It was shown …

Cross Talk between Adipose Tissue and Placenta in Obese and Gestational Diabetes Mellitus Pregnancies via Exosomes

N Jayabalan, S Nair, Z Nuzhat, GE Rice… - Frontiers in …, 2017 - frontiersin.org
Obesity is an important public health issue worldwide, where it is commonly associated with
the development of metabolic disorders, especially insulin resistance (IR). Maternal obesity …

Intercellular and interorgan crosstalk through adipocyte extracellular vesicles

C Crewe, PE Scherer - Reviews in Endocrine and Metabolic Disorders, 2022 - Springer
Functional adipose tissue is essential for homeostatic maintenance of systemic metabolism.
As such, adipose tissue dysfunction, like that seen in the obese state, directly contributes to …

Extracellular vesicles from adipose tissue—a potential role in obesity and type 2 diabetes?

X Gao, C Salomon, DJ Freeman - Frontiers in endocrinology, 2017 - frontiersin.org
Adipose tissue plays a key role in the development of insulin resistance and its pathological
sequelae, such as type 2 diabetes and non-alcoholic fatty liver disease. Dysfunction in the …

Сахарный диабет: современное состояние вопроса (часть 1)

МУ Шарофова, ШС Сагдиева, СД Юсуфи - Вестник Авиценны, 2019 - cyberleninka.ru
Авторами проведён анализ многочисленных научных исследований, касающихся
проблемы сахарного диабета II типа, масштабы распространения которого вызывают …

Adiponectin and its isoforms in pathophysiology

M van Andel, AC Heijboer, ML Drent - Advances in clinical chemistry, 2018 - Elsevier
Adiponectin circulates in blood in multiple isoforms. High molecular weight (HMW)
adiponectin is thought to be most biologically active and promotes glucose uptake, insulin …

The Effect of Marine Derived n-3 Fatty Acids on Adipose Tissue Metabolism and Function

M Todorčević, L Hodson - Journal of clinical medicine, 2015 - mdpi.com
Adipose tissue function is key determinant of metabolic health, with specific nutrients being
suggested to play a role in tissue metabolism. One such group of nutrients are the n-3 fatty …