ctDNA as a cancer biomarker: A broad overview

LS Pessoa, M Heringer, VP Ferrer - Critical reviews in oncology …, 2020 - Elsevier
Circulating tumor DNA (ctDNA) in fluids has gained attention because ctDNA seems to
identify tumor-specific abnormalities, which could be used for diagnosis, follow-up of …

Translational application of circulating DNA in oncology: review of the last decades achievements

NO Tuaeva, L Falzone, YB Porozov, AE Nosyrev… - Cells, 2019 - mdpi.com
In recent years, the introduction of new molecular techniques in experimental and clinical
settings has allowed researchers and clinicians to propose circulating-tumor DNA (ctDNA) …

TP53 co-mutations in advanced EGFR-mutated non–small cell lung cancer: Prognosis and therapeutic strategy for cancer therapy

S Liu, J Yu, H Zhang, J Liu - Frontiers in oncology, 2022 - frontiersin.org
Lung cancer is the leading cause of cancer-related deaths worldwide. As the most prevalent
molecular mutation subtypes in non-small cell lung cancer (NSCLC), EGFR-TKIs are …

A literature review of microRNA and gene signaling pathways involved in the apoptosis pathway of lung cancer

H Abolfathi, M Arabi, M Sheikhpour - Respiratory Research, 2023 - Springer
Background Lung cancer is one of the leading causes of death in the world and the
deadliest of all cancers. Apoptosis is a key pathway in regulating the cell growth rate …

Validation of a liquid biopsy assay with molecular and clinical profiling of circulating tumor DNA

JD Finkle, H Boulos, TM Driessen, C Lo… - NPJ Precision …, 2021 - nature.com
Liquid biopsy is a valuable precision oncology tool that is increasingly used as a non-
invasive approach to identify biomarkers, detect resistance mutations, monitor disease …

Optical nanomaterial-based detection of biomarkers in liquid biopsy

YJ Kim, WY Rho, S Park, BH Jun - Journal of Hematology & Oncology, 2024 - Springer
Liquid biopsy, which is a minimally invasive procedure as an alternative to tissue biopsy,
has been introduced as a new diagnostic/prognostic measure. By screening disease-related …

[HTML][HTML] GLUT1/3/4 as novel biomarkers for the prognosis of human breast cancer

K Zeng, G Ju, H Wang, J Huang - Translational cancer research, 2020 - ncbi.nlm.nih.gov
Background Anomalous expression of glucose transporters (GLUTs) has been observed in
a variety of tumor tissues. Although GLUT factors have been shown to have prognostic value …

[HTML][HTML] Circulating tumour DNA analysis for early detection of lung cancer: a systematic review

WKJ Lam, J Bai, MJL Ma, YTT Cheung… - Annals of Translational …, 2024 - ncbi.nlm.nih.gov
Background Circulating tumor DNA (ctDNA) analysis has been applied in cancer
diagnostics including lung cancer. Specifically for the early detection purpose, various …

The Polemic Diagnostic Role of TP53 Mutations in Liquid Biopsies from Breast, Colon and Lung Cancers

MC Garrido-Navas, A García-Díaz, MP Molina-Vallejo… - Cancers, 2020 - mdpi.com
Simple Summary Most solid tumors share mutations in TP53 that is thus considered one of
the main cancer driver genes. Mutations in TP53 occur very early during tumor development …

Advances in the detection technologies and clinical applications of circulating tumor DNA in metastatic breast cancer

H Liao, H Li - Cancer Management and Research, 2020 - Taylor & Francis
Breast cancer (BC) represents the most commonly diagnosed cancer among females
worldwide. Although targeted therapy has greatly improved the efficacy of treating BC, a …