Neuroinflammation and oxidative stress in the pathogenesis of autism spectrum disorder

N Usui, H Kobayashi, S Shimada - International Journal of Molecular …, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder (NDD) characterized by
impairments in social communication, repetitive behaviors, restricted interests, and …

Maternal immune activation as an epidemiological risk factor for neurodevelopmental disorders: Considerations of timing, severity, individual differences, and sex in …

MB Hall, DE Willis, EL Rodriguez… - Frontiers in …, 2023 - frontiersin.org
Epidemiological evidence suggests that one's risk of being diagnosed with a
neurodevelopmental disorder (NDD)—such as autism, ADHD, or schizophrenia—increases …

Genetic variants associated with psychiatric disorders are enriched at epigenetically active sites in lymphoid cells

ME Lynall, B Soskic, J Hayhurst… - Nature …, 2022 - nature.com
Multiple psychiatric disorders have been associated with abnormalities in both the innate
and adaptive immune systems. The role of these abnormalities in pathogenesis, and …

Maternal infection during pregnancy and likelihood of autism and intellectual disability in children in Sweden: a negative control and sibling comparison cohort study

M Brynge, H Sjöqvist, RM Gardner, BK Lee… - The Lancet …, 2022 - thelancet.com
Background Maternal infections during pregnancy are associated with intellectual disability
and autism in exposed children. Whether these associations are causal, and therefore …

[HTML][HTML] The gut-brain connection: Exploring the influence of the gut microbiota on neuroplasticity and neurodevelopmental disorders

F Damiani, S Cornuti, P Tognini - Neuropharmacology, 2023 - Elsevier
Neuroplasticity refers to the ability of brain circuits to reorganize and change the properties
of the network, resulting in alterations in brain function and behavior. It is traditionally …

Prenatal environmental risk factors for autism spectrum disorder and their potential mechanisms

C Love, L Sominsky, M O'Hely, M Berk, P Vuillermin… - BMC medicine, 2024 - Springer
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is globally
increasing in prevalence. The rise of ASD can be partially attributed to diagnostic expansion …

[HTML][HTML] Inflammatory conditions during pregnancy and risk of autism and other neurodevelopmental disorders

LA Croen, JL Ames, Y Qian, S Alexeeff… - … psychiatry global open …, 2024 - Elsevier
Background Maternal inflammation can result from immune dysregulation and metabolic
perturbations during pregnancy. Whether conditions associated with inflammation during …

Beyond TORCH: A narrative review of the impact of antenatal and perinatal infections on the risk of disability

M Devaraju, A Li, S Ha, M Li, M Shivakumar, H Li… - Neuroscience & …, 2023 - Elsevier
Infections and inflammation during pregnancy or early life can alter child neurodevelopment
and increase the risk for structural brain abnormalities and mental health disorders. There is …

Sex-based differences in placental DNA methylation profiles related to gestational age: an NIH ECHO meta-analysis

CM Bulka, TM Everson, AA Burt, CJ Marsit… - Epigenetics, 2023 - Taylor & Francis
The placenta undergoes many changes throughout gestation to support the evolving needs
of the foetus. There is also a growing appreciation that male and female foetuses develop …

Characterizing the neuroimmune environment of offspring in a novel model of maternal allergic asthma and particulate matter exposure

JM Tamayo, HC Osman, JJ Schwartzer… - Journal of …, 2023 - Springer
Inflammation during pregnancy is associated with an increased risk for neurodevelopmental
disorders (NDD). Increased gestational inflammation can be a result of an immune …