The medial frontal cortex and adjacent orbitofrontal cortex have been the focus of
investigations of decision-making, behavioral flexibility, and social behavior. We review …

The prefrontal cortex (PFC) plays a critical role in the generation and regulation of emotion.
However, we lack an integrative framework for understanding how different emotion-related …

Statistical regularities in the environment create prior beliefs that we rely on to optimize our
behavior when sensory information is uncertain. Bayesian theory formalizes how prior …

Behavioral control is not unitary. It comprises parallel systems, model based and model free,
that respectively generate flexible and habitual behaviors. Model-based decisions use …

Despite being considered primarily a mood disorder, major depressive disorder (MDD) is
characterized by cognitive and decision making deficits. Recent research has employed …

INTRODUCTION Everyday life often requires arbitrating between pursuing an ongoing
action plan by possibly adjusting it versus exploring new action plans instead. Resolving this …

A cornerstone of successful social interchange is the ability to anticipate each other's
intentions or actions. While generating these internal predictions is essential for constructive …

Social neuroscience aims to describe the neural systems that underpin social cognition and
behaviour. Over the past decade, researchers have begun to combine computational …

Neural mechanisms that mediate the ability to make value-guided decisions have received
substantial attention in humans and animals,,,,–. Experiments in animals typically involve …

Abstract ARNSTEN, AFT, MKP Joyce and AC Roberts. The Aversive Lens: Stress effects on
the prefrontal-cingulate cortical pathways that regulate emotion. NEUROSCI BIOBEHAV …