Molecular mechanism of lncRNAs in pathogenesis and diagnosis of auto-immune diseases, with a special focus on lncRNA-based therapeutic approaches
Autoimmune diseases are a diverse set of conditions defined by organ damage due to
abnormal innate and acquired immune system responses. The pathophysiology of …
abnormal innate and acquired immune system responses. The pathophysiology of …
[HTML][HTML] Long non-coding RNAs and their “discrete” contribution to IBD and Johne's disease—what stands out in the current picture? A comprehensive review
KA Triantaphyllopoulos - International Journal of Molecular Sciences, 2023 - mdpi.com
Non-coding RNAs (ncRNA) have paved the way to new perspectives on the regulation of
gene expression, not only in biology and medicine, but also in associated fields and …
gene expression, not only in biology and medicine, but also in associated fields and …
Artificial intelligence and high-dimensional technologies in the theragnosis of systemic lupus erythematosus
Systemic lupus erythematosus is a complex, systemic autoimmune disease characterised by
immune dysregulation. Pathogenesis is multifactorial, contributing to clinical heterogeneity …
immune dysregulation. Pathogenesis is multifactorial, contributing to clinical heterogeneity …
[HTML][HTML] Roles of lncRNAs in NF-κB-Mediated Macrophage Inflammation and Their Implications in the Pathogenesis of Human Diseases
JJ Shin, J Park, HS Shin, I Arab, K Suk… - International Journal of …, 2024 - mdpi.com
Over the past century, molecular biology's focus has transitioned from proteins to DNA, and
now to RNA. Once considered merely a genetic information carrier, RNA is now recognized …
now to RNA. Once considered merely a genetic information carrier, RNA is now recognized …
Differential lncRNA profiles of blood plasma-derived exosomes from systemic lupus erythematosus
X Peng, L Ma, J Miao, S Xu, Z Shuai - Gene, 2024 - Elsevier
Abstract Introduction Long non-coding RNAs (lncRNAs) dysregulation is key in the
pathogenesis of systemic lupus erythematosus (SLE), but the role of exosomal lncRNAs in …
pathogenesis of systemic lupus erythematosus (SLE), but the role of exosomal lncRNAs in …
[HTML][HTML] lncRNA Biomarkers of Glioblastoma Multiforme
M Pokorná, M Černá, S Boussios, SV Ovsepian… - Biomedicines, 2024 - mdpi.com
Long noncoding RNAs (lncRNAs) are RNA molecules of 200 nucleotides or more in length
that are not translated into proteins. Their expression is tissue-specific, with the vast majority …
that are not translated into proteins. Their expression is tissue-specific, with the vast majority …
Association of rs12826786 and rs1899663, Long Non-coding RNA HOTAIR Polymorphic Variants, with Susceptibility to Rheumatoid Arthritis Disease
Z Sadeghi, MJ Mokhtari - Indian Journal of Clinical Biochemistry, 2024 - Springer
The most prevalent inflammatory arthropathy in the world is rheumatoid arthritis (RA). An
essential part of the pathogenesis of RA involves autoimmune responses. Variants in …
essential part of the pathogenesis of RA involves autoimmune responses. Variants in …
LncRNAs Affecting NF-κB-Mediated Macrophage Inflammation Are Potential Therapeutic Targets in Human Diseases
The studies regarding macrophage lncRNAs described in this review can help provide
valuable information for developing treatments for various pathological conditions involving …
valuable information for developing treatments for various pathological conditions involving …