The gut microbiome lies at the intersection between the environment and the host, with the
ability to modify host responses to disease-relevant exposures and stimuli. This is evident in …

Short chain fatty acids (SCFAs), mainly including acetate, propionate and butyrate, are
produced by intestinal bacteria during the fermentation of partially digested and indigestible …

The intestine is the largest peripheral lymphoid organ in animals, including humans, and
interacts with a vast array of microorganisms called the gut microbiota. Comprehending the …

The gut microbiota and its metabolites have been shown to play a pivotal role in the
regulation of metabolic, endocrine and immune functions. Though the exact mechanism of …

The gut microbiota encodes a broad range of enzymes capable of synthetizing various
metabolites, some of which are still uncharacterized. One well-known class of microbiota …

Insights into the relationship between immunometabolism and inflammation have enabled
the targeting of several immunity-mediated inflammatory processes that underlie infectious …

The global incidence of Chronic Kidney Disease (CKD) is steadily escalating, with
discernible linkage to the intricate terrain of intestinal microecology. The intestinal microbiota …

Obesity and chronic low-grade inflammation, often occurring together, significantly
contribute to severe metabolic and inflammatory conditions like type 2 diabetes (T2D) …

Nonpathogenic commensal microbiota and their metabolites and components are essential
to maintain a tolerogenic environment and promote beneficial health effects. The metabolic …

Gut microbiota is generally considered to play an important role in host health due to its
extensive immunomodulatory activities. Th17 and Treg cells are two important CD4+ T cell …