Antibodies that are present in the serum of healthy individuals in the absence of deliberate
immunization with any antigen, are refered to as natural antibodies. A vast majority of natural …

Intravenous immunoglobulin (IVIg) is therapeutically used in a variety of immune-mediated
diseases. The beneficial effects of IVIg in auto-antibody-mediated diseases can be …

The clinical use of intravenous immunoglobulin (IVIg) based on its immunomodulatory and
anti-inflammatory potential remains an ongoing challenge. Fcγ receptor-mediated effects of …

The rodent model for multiple sclerosis, experimental allergic (autoimmune)
encephalomyelitis (EAE), has been used to dissect molecular mechanisms of the …

Intravenous immunoglobulin (IVIg) is used to treat patients with primary antibody
deficiencies and, at high doses, to treat a range of autoimmune and inflammatory disorders …

In the present study, the mechanisms and importance of the Fc portion of immunoglobulin in
experimental giant cell myocarditis were examined. Giant cell myocarditis was induced in …

Despite an increasing use of high-dose therapy of iv gammaglobulin (IVIg) in the treatment
of various T cell–and Ab-mediated inflammatory and autoimmune diseases, comprehension …

Immunoglobulins (Ig) or antibodies are heavy plasma proteins, with sugar chains added to
amino-acid residues by N-linked glycosylation and occasionally by O-linked glycosylation …

Study of models of ocular autoimmunity and of autoimmune uveitis in humans has lead to a
shift in the perceived nature of immune privilege from one based on anatomical isolation of …

Intravenous immunoglobulin (IVIg) is a polyclonal immunoglobulin G preparation with potent
immunomodulatory properties. The mode of action of IVIg has been investigated in multiple …