The human arylamine N-acetyltransferases first attracted attention because of their role in
drug metabolism. However, much of the current literature has focused on their role in the …

The arylamine N-acetyltransferase (NAT) nomenclature committee assigns functional
phenotypes for human arylamine N-acetyltransferase 1 (NAT1) alleles in those instances in …

Arylamine N-acetyltransferases (NAT) are important enzymes involved in the metabolic
activation of aromatic and heterocyclic amines and inhibitors of NAT enzymes may be …

Background: Glutathione-S-transferases (GSTs) and N-acetyltransferases (NATs) are
involved in the metabolism of a wide range of carcinogenic chemicals. Allelic polymorphism …

Human CYP1A2 and arylamine N-acetyltransferases, which are encoded by the
polymorphic CYP1A2 and NAT genes respectively, have been shown to have wide …

Purpose Chronic exposure to pesticides has been associated with thyroid dysfunction owing
to their endocrine disruption ability. Genetic variations in genes encoding phase I and II …

Background Although several studies have shown that drug metabolizing enzyme gene
polymorphisms may influence the impact of therapy in childhood leukemia, no …

AIM: To evaluate the effect of inflammatory cytokines on arylamine N-acetyltransferase 1
(NAT1), which is a phase-II enzyme involved in the biotransformation of aromatic and …

BACKGROUND: We investigated the arylamine N-acetyltransferase-1 (NAT1) gene
polymorphisms and the correlation between genotype and phenotype in a Chinese Han …

Heterocyclic aromatic amines (HAAs), carcinogens produced in meat when cooked at high
temperatures, are an emerging biologic explanation for the meat‐colorectal cancer …