Antimicrobial peptides (AMPs) are regarded as a new generation of antibiotics. Besides
antimicrobial activity, AMPs also have antibiofilm, immune-regulatory, and other activities …

Host defence peptides (HDPs) are integral components of innate immunity across all living
organisms. These peptides can exert direct antibacterial effects, targeting planktonic cells …

The antibiotic crisis has led to a pressing need for alternatives such as antimicrobial
peptides (AMPs). Recent work has shown that these molecules have great potential not only …

Current research has demonstrated that small cationic amphipathic peptides have strong
potential not only as antimicrobials, but also as antibiofilm agents, immune modulators, and …

Microbes are known to colonize surfaces and form biofilms. These biofilms are communities
of microbes encased in a self-produced matrix that often contains polysaccharides, DNA and …

Despite efforts to develop new antibiotics, antibacterial resistance still develops too fast for
drug discovery to keep pace. Often, resistance against a new drug develops even before it …

With the antibiotic development pipeline running dry, many fear that we might soon run out
of treatment options. High-density infections are particularly difficult to treat due to their …

Microbial biofilms, which are elaborate and highly resistant microbial aggregates formed on
surfaces or medical devices, cause two-thirds of infections and constitute a serious threat to …

Clinical management of Staphylococcus aureus infections presents a challenge due to the
high incidence, considerable virulence, and emergence of drug resistance mechanisms …

Highly antibiotic resistant, microbial communities, referred to as biofilms, cause various life-
threatening infections in humans. At least two-thirds of all clinical infections are biofilm …