The mitochondrion relies on compartmentalization of certain enzymes, ions and metabolites
for the sake of efficient metabolism. In order to fulfil its activities, a myriad of carriers are …

In mammals, the central clock localized in the central nervous system imposes a circadian
rhythmicity to all organs. This is achieved thanks to a well‐conserved molecular clockwork …

Background This work describes the first genome-wide analysis of the transcriptional
landscape of the pig. A new porcine Affymetrix expression array was designed in order to …

Background Thoroughbred horses have been selected for traits contributing to speed and
stamina for centuries. It is widely recognized that inherited variation in physical and …

Selective breeding for speed in the racehorse has resulted in an unusually high frequency of
the C-variant (g. 66493737C/T) at the myostatin gene (MSTN) in cohorts of the …

Background Thoroughbred horses are the most expensive domestic animals, and their
running ability and knowledge about their muscle-related diseases are important in animal …

Global gene expression profiling by RNA-Sequencing (RNA-Seq) was introduced in 2004
with the advent of next generation sequencing technologies and has made a revolutionary …

Exercise is beneficial for a variety of age-related disorders. However, the molecular
mechanisms mediating the beneficial adaptations to exercise in older adults are not well …

A horse's success on the racetrack is determined by genetics, training and nutrition, and
their translation into physical traits such as speed, endurance and muscle strength …

The athletic horse, despite being over 50% muscle mass, remains understudied with regard
to the effects of exercise and training on skeletal muscle metabolism. To begin to address …