Defects in chromatin modifiers and remodelers have been described both for hematological
and solid malignancies, corroborating and strengthening the role of epigenetic aberrations …

Proteins and RNA functionally and physically intersect in multiple biological processes,
however, currently no universal method is available to purify protein-RNA complexes. Here …

Gene expression in higher eukaryotic cells orchestrates interactions between thousands of
RNA-binding proteins (RBPs) and tens of thousands of RNAs. The kinetics by which RBPs …

With the maturing techniques for advanced synthesis and engineering of two-dimensional
(2D) materials, its nanocomposites, hybrid nanostructures, alloys, and heterostructures …

The increased threats of pathogenic bioaerosol make air disinfection in heating, ventilation,
and air conditioning (HVAC) systems crucial to occupants' health. To satisfy the high …

Many tumors express meiotic genes that could potentially drive somatic chromosome
instability. While germline cohesin subunits SMC1B, STAG3, and REC8 are widely …

The identification of transcription factor (TF) binding sites in the genome is critical to
understanding gene regulatory networks (GRNs). While ChIP-seq is commonly used to …

Identification of DNA–protein binding sites in protein sequence plays an essential role in a
wide variety of biological processes. In particular, there are huge volumes of protein …

Interactions between double-stranded RNA (dsRNA) and proteins play an important role in
cellular homeostasis by regulating the editing, stability, and splicing of intracellular RNA …

RNA− protein interactions play a pivotal role in cell homeostasis and disease, but current
approaches to study them require a considerable amount of starting material, favor the …