Inorganic phosphate (Pi) plays a critical function in many tissues of the body: for example, as
part of the hydroxyapatite in the skeleton and as a substrate for ATP synthesis. Pi is the main …

The importance of phosphate homeostasis in chronic kidney disease (CKD) has been
recognized for decades, but novel insights—which are frequently relevant to everyday …

Inorganic phosphate (Pi) is essential for signal transduction and cell metabolism, and is also
an essential structural component of the extracellular matrix of the skeleton. Pi is sensed in …

Osteoporosis is a complex multifactorial disorder of the skeleton. Genetic factors are
important in determining peak bone mass and structure, as well as the predisposition to …

Several microRNAs (miRNAs) have been linked to chronic kidney disease (CKD) mortality,
cardiovascular (CV) complications and kidney disease progression. However, their …

Chronic kidney disease (CKD), which is characterized by the gradual loss of kidney function,
is a growing worldwide problem due to CKD-related morbidity and mortality. There are no …

Vascular calcification is the ectopic deposition of calcium hydroxyapatite minerals in arterial
wall, which involves the transdifferentiation of vascular smooth muscle cells (VSMCs) toward …

Context WNT signaling is fundamental to bone health, and its aberrant activation leads to
skeletal pathologies. The heterozygous missense mutation p. C218G in WNT1, a key WNT …

Aim: The purpose of this review was to evaluate the expression patterns of miRNAs in
periodontal and peri-implant diseases, while identifying potential miRNAs with the greatest …

Patients with chronic kidney disease (CKD) have an elevated prevalence of atheromatous
(ATH) and/or non-atheromatous (non-ATH) cardiovascular disease (CVD) due to an array of …