Large serine recombinases (LSRs) are DNA integrases that facilitate the site-specific
integration of mobile genetic elements into bacterial genomes. Only a few LSRs, such as …

Serine integrases are phage-(or mobile element-) encoded enzymes that catalyse site-
specific recombination reactions between a short DNA sequence on the phage genome …

Tethered particle motion/microscopy (TPM) is a biophysical tool used to analyze changes in
the effective length of a polymer, tethered at one end, under changing conditions. The tether …

Genetic exchange mediated by viruses of bacteria (bacteriophages) is the primary driver of
rapid bacterial evolution. The priority of viruses is usually to propagate themselves. Most …

Recent microbial genome sequencing efforts have revealed a vast reservoir of mobile
genetic elements containing integrases that could be useful genome engineering tools …

Serine integrases (Ints) are a family of site-specific recombinases (SSRs) encoded by some
bacteriophages to integrate their genetic material into the genome of a host. Their ability to …

Owing to the threats that Salmonella poses to public health and the abuse of antimicrobials,
bacteriophage therapy against Salmonella is experiencing a resurgence. Although several …

Large serine integrases are phage-(or mobile element-) encoded enzymes that catalyse site-
specific recombination reactions between a short DNA sequence on the phage genome …

In Bacillus subtilis, a sporulation‐related gene, spsM, is disrupted by SPβ prophage, but
reconstituted during sporulation through SPβ excision. The spsM reconstitution is catalyzed …

Recombination directionality factors (RDFs) for large serine integrases (LSIs) are cofactor
proteins that control the directionality of recombination to favor excision over insertion …