Reticular pseudodrusen: a critical phenotype in age-related macular degeneration

Z Wu, EL Fletcher, H Kumar, U Greferath… - Progress in retinal and …, 2022 - Elsevier
Reticular pseudodrusen (RPD), or subretinal drusenoid deposits (SDD), refer to distinct
lesions that occur in the subretinal space. Over the past three decades, their presence in …

Fluctuations in central subfield thickness associated with worse visual outcomes in patients with diabetic macular edema in clinical trial setting

MR Starr, M Salabati, R Mahmoudzadeh… - American Journal of …, 2021 - Elsevier
Purpose This study examines the relationship between fluctuations in central subfield
thickness (CST) and visual acuity (VA) in patients with diabetic macular edema (DME) using …

Early stages of age-related macular degeneration: racial/ethnic differences and proposal of a new classification incorporating emerging concept of choroidal …

M Sasaki, R Kawasaki, Y Yanagi - Journal of clinical medicine, 2022 - mdpi.com
The progression of age-related macular degeneration (AMD) is determined by
environmental and genetic factors, and phenotypic or molecular risk factors have been …

[HTML][HTML] Reticular pseudodrusen are associated with more advanced para-central photoreceptor degeneration in intermediate age-related macular degeneration

M Trinh, N Eshow, D Alonso-Caneiro… - … & Visual Science, 2022 - tvst.arvojournals.org
Purpose: The purpose of this study was to examine retinal topographical differences
between intermediate age-related macular degeneration (iAMD) with reticular …

[HTML][HTML] Exploring reticular pseudodrusen extent and impact on mesopic visual sensitivity in intermediate age-related macular degeneration

H Kumar, RH Guymer, LAB Hodgson… - … & Visual Science, 2022 - tvst.arvojournals.org
Purpose: To explore the impact of the extent of reticular pseudodrusen (RPD) on mesopic
visual sensitivity in individuals with intermediate age-related macular degeneration (AMD) …

Repeatability of quantitative measurements of retinal layers with SD-OCT and agreement between vertical and horizontal scan protocols in healthy eyes

A Dominguez-Vicent, R Brautaset, AP Venkataraman - PLoS One, 2019 - journals.plos.org
Purpose To evaluate the repeatability of the new spectral domain optical coherence
tomography (HOCT-1F), and also to evaluate the agreement between vertical and horizontal …

LeptoVitelliform Maculopathy: delineating a distinct clinical entity from acquired vitelliform lesions

S Fragiotta, M Parravano, R Sacconi, MS Polito… - Eye, 2024 - nature.com
Objectives To characterize acquired vitelliform lesions associated with leptochoroid (ie,
diffuse choroidal thinning) and reticular pseudodrusen (RPD) and compare this phenotype …

The first-year variation in central retinal thickness predicts legal blindness in patients with neovascular age-related macular degeneration

Y Guo, J Wu, X Zheng, C Yin, Z Wu - Ophthalmic Research, 2023 - karger.com
Introduction: Due to its progressive nature, early evaluation and timely prediction of legal
blindness are important in patients with neovascular age-related macular degeneration …

Macular functional and morphological changes in intermediate age-related maculopathy

V Parisi, L Ziccardi, E Costanzo… - … & Visual Science, 2020 - iovs.arvojournals.org
Purpose: The purpose of this study was to evaluate macular preganglionic function and to
verify its relationship with retinal and choroidal morphology in patients with intermediate age …

Use of composite end points in early and intermediate age-related macular degeneration clinical trials: state-of-the-art and future directions

JH Terheyden, S Schmitz-Valckenberg, DP Crabb… - …, 2021 - karger.com
The slow progression of early age-related macular degeneration (AMD) stages to advanced
AMD requires the use of surrogate end points in clinical trials. The use of combined end …