European Academy of Andrology (EAA) guidelines on investigation, treatment and monitoring of functional hypogonadism in males: Endorsing organization …

G Corona, DG Goulis, I Huhtaniemi, M Zitzmann… - …, 2020 - Wiley Online Library
Background Evidence regarding functional hypogonadism, previously referred to as 'late‐
onset'hypogonadism, has increased substantially during the last 10 year. Objective To …

A reappraisal of testosterone's binding in circulation: physiological and clinical implications

AL Goldman, S Bhasin, FCW Wu, M Krishna… - Endocrine …, 2017 - academic.oup.com
In the circulation, testosterone and other sex hormones are bound to binding proteins, which
play an important role in regulating their transport, distribution, metabolism, and biological …

Low testosterone levels predict clinical adverse outcomes in SARS‐CoV‐2 pneumonia patients

G Rastrelli, V Di Stasi, F Inglese, M Beccaria… - …, 2021 - Wiley Online Library
Background The pandemic of new severe acute respiratory syndrome (SARS) due to
coronavirus (CoV) 2 (SARS‐CoV‐2) has stressed the importance of effective diagnostic and …

Testosterone therapy in men with hypogonadism: an endocrine society clinical practice guideline

S Bhasin, JP Brito, GR Cunningham… - The Journal of …, 2018 - academic.oup.com
Abstract Objective To update the “Testosterone Therapy in Men With Androgen Deficiency
Syndromes” guideline published in 2010. Participants The participants include an Endocrine …

Evaluation and management of testosterone deficiency: AUA guideline

JP Mulhall, LW Trost, RE Brannigan, EG Kurtz… - The Journal of …, 2018 - auajournals.org
Purpose: There has been a marked increase in testosterone prescriptions in the past
decade resulting in a growing need to give practicing clinicians proper guidance on the …

American Association of Clinical Endocrinologists and American College of Endocrinology comprehensive clinical practice guidelines for medical care of patients with …

WT Garvey, JI Mechanick, EM Brett, AJ Garber… - Endocrine Practice, 2016 - Elsevier
Objective Development of these guidelines is mandated by the American Association of
Clinical Endocrinologists (AACE) Board of Directors and the American College of …

3β-Hydroxysteroid dehydrogenase expressed by gut microbes degrades testosterone and is linked to depression in males

D Li, R Liu, M Wang, R Peng, S Fu, A Fu, J Le, Q Yao… - Cell host & …, 2022 - cell.com
Testosterone deficiency can lead to depressive symptoms in humans; however, the causes
of this deficiency are incompletely understood. Here, we isolated Mycobacterium neoaurum …

Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline

S Bhasin, GR Cunningham, FJ Hayes… - The Journal of …, 2010 - academic.oup.com
Objective: Our objective was to update the guidelines for the evaluation and treatment of
androgen deficiency syndromes in adult men published previously in 2006. Participants …

[HTML][HTML] Identification of late-onset hypogonadism in middle-aged and elderly men

FCW Wu, A Tajar, JM Beynon, SR Pye… - … England Journal of …, 2010 - Mass Medical Soc
Background The association between aging-related testosterone deficiency and late-onset
hypogonadism in men remains a controversial concept. We sought evidence-based criteria …

The role of adiponectin in cancer: a review of current evidence

M Dalamaga, KN Diakopoulos… - Endocrine …, 2012 - academic.oup.com
Improving physical function and mobility in a continuously expanding elderly population
emerges as a high priority of medicine today. Muscle mass, strength/power, and maximal …