Global virus outbreaks: Interferons as 1st responders

BX Wang, EN Fish - Seminars in immunology, 2019 - Elsevier
Outbreaks of severe virus infections with the potential to cause global pandemics are
increasing. In many instances these outbreaks have been newly emerging (SARS …

COVID‐19‐induced autoimmune thyroiditis: Exploring molecular mechanisms

B Mohammadi, K Dua, M Saghafi… - Journal of medical …, 2023 - Wiley Online Library
Severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) damages multiple
organs, including the thyroid, by direct invasion and cell entry via angiotensin‐converting …

An M1-like macrophage polarization in decidual tissue during spontaneous preterm labor that is attenuated by rosiglitazone treatment

Y Xu, R Romero, D Miller, L Kadam, TN Mial… - The Journal of …, 2016 - journals.aai.org
Decidual macrophages are implicated in the local inflammatory response that accompanies
spontaneous preterm labor/birth; however, their role is poorly understood. We hypothesized …

[HTML][HTML] IP-10 is highly involved in HIV infection

J Lei, X Yin, H Shang, Y Jiang - Cytokine, 2019 - Elsevier
Abstract Interferon-γ (IFN-γ)-induced protein 10 (IP-10 or CXCL-10) is a chemokine involved
in trafficking immune cells to inflammatory sites. Numerous studies have reported …

Th1 chemokines in autoimmune endocrine disorders

P Fallahi, SM Ferrari, F Ragusa, I Ruffilli… - The Journal of …, 2020 - academic.oup.com
Context The CXC chemokine receptor CXCR3 and its chemokines CXCL10, CXCL9, and
CXCL11 are implicated in the pathogenesis of autoimmune diseases. Here, we review these …

Macrophages in human colorectal cancer are pro‐inflammatory and prime T cells towards an anti‐tumour type‐1 inflammatory response

SM Ong, YC Tan, O Beretta, D Jiang… - European journal of …, 2012 - Wiley Online Library
High macrophage infiltration into tumours often correlates with poor prognoses; in colorectal,
stomach and skin cancers, however, the opposite is observed but the mechanisms behind …

[HTML][HTML] Chemokines in thyroid autoimmunity

SM Ferrari, SR Paparo, F Ragusa, G Elia… - Best Practice & …, 2023 - Elsevier
The chemokine receptor CXCR3 and its chemokines CXCL9, CXCL10, and CXCL11 are
involved in the pathogenesis of autoimmune diseases. Th1 lymphocytes are recruited by …

Cytokines as targets of novel therapies for Graves' ophthalmopathy

P Fallahi, SM Ferrari, G Elia, F Ragusa… - Frontiers in …, 2021 - frontiersin.org
Graves' disease (GD) is an organ-specific autoimmune disorder of the thyroid, which is
characterized by circulating TSH-receptor (TSH-R) stimulating antibodies (TSAb), leading to …

[HTML][HTML] ATM inhibition augments type I interferon response and antitumor T-cell immunity when combined with radiation therapy in murine tumor models

WJ Jin, LM Zangl, M Hyun, E Massoud… - … for Immunotherapy of …, 2023 - ncbi.nlm.nih.gov
Background Radiation therapy (RT) elicits DNA double-strand breaks, resulting in tumor
cytotoxicity and a type I interferon (IFN) response via stimulator of interferon genes (STING) …

[HTML][HTML] Chemokines in hyperthyroidism

SM Ferrari, I Ruffilli, G Elia, F Ragusa… - Journal of clinical & …, 2019 - Elsevier
The term “hyperthyroidism” indicates a condition due to an exaggerate production of thyroid
hormone; the most frequent cause is Graves' disease (GD). We review cytokines and …