Pyrrolopyrimidine compounds as inhibitors of CDK4/6

CT Brain, YS Cho, JW Giraldes, B Lagu… - US Patent …, 2015 - Google Patents
2012-08-16 Assigned to NOVARTIS AG reassignment NOVARTIS AG ASSIGNMENT OF
ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: LAGU, BHARAT …

Pyrrolopyrimidine compounds as inhibitors of CDK4/6

CT Brain, YS Cho, JW Giraldes, B Lagu… - US Patent …, 2016 - Google Patents
0 C*[2*][Y].[1*] N1C (C (= O) N ([4*]) C ([8*])([9*])[10*])= CC2= C1N= C (NC1= N*= CC= C1)
N= C2.[11*] C Chemical compound C*[2*][Y].[1*] N1C (C (= O) N ([4*]) C ([8*])([9*])[10*]) …

Pharmaceutical combinations comprising (a) the cyclin dependent kinase 4/6 (cdk4/6) inhibitor lee011 (= ribociclib), and (b) the epidermal growth factor receptor (egfr) …

G Caponigro, HS Thomas, J Lehar - 2019 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
56896739&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Pharmaceutical combination comprising binimetinib

G Caponigro, S Delach, S Doshi, HS Thomas… - US Patent …, 2018 - Google Patents
US9867825B2 - Pharmaceutical combination comprising binimetinib - Google Patents
US9867825B2 - Pharmaceutical combination comprising binimetinib - Google Patents …

Combination therapies for the treatment of breast cancer

M KORPAL, N RIOUX, PG Smith - 2018 - Google Patents
WO2018170447A1 - Combination therapies for the treatment of breast cancer - Google Patents
WO2018170447A1 - Combination therapies for the treatment of breast cancer - Google Patents …

Ribociclib intermediate and preparation method therefor

X Xu - US Patent 10,005,726, 2018 - Google Patents
BACKGROUND ART 25 Ribociclib is a high-specificity cell cycle-dependent kinase
(CDK4/6) inhibitor which is developed by the Novar tis Company and is orally effective, and …

Combination therapies for the treatment of breast cancer

M KORPAL, N RIOUX, PG Smith - US Patent 11,083,722, 2021 - Google Patents
US11083722B2 - Combination therapies for the treatment of breast cancer - Google Patents
US11083722B2 - Combination therapies for the treatment of breast cancer - Google Patents …

Combination therapies for the treatment of hepatocellular carcinoma

A SELVARAJ, P Smith - 2018 - Google Patents
WO2018039324A1 - Combination therapies for the treatment of hepatocellular carcinoma -
Google Patents WO2018039324A1 - Combination therapies for the treatment of hepatocellular …