Osteoarthritis (OA), the commonest arthritis, is characterized by the progressive destruction
of cartilage, leading to disability. The Current early clinical treatment strategy for OA often …

Chemotactic cytokines—chemokines—control immune cell migration in the process of
initiation and resolution of inflammatory conditions as part of the body's defense system …

Activation of endothelium and immune cells is fundamental to the initiation of autoimmune
diseases such as rheumatoid arthritis (RA), and it results in trans-endothelial cell migration …

Rheumatoid arthritis (RA) is a classic autoimmune disease characterized by uncontrolled
synovial proliferation, pannus formation, cartilage injury, and bone destruction. The specific …

Control of excessive mitochondrial oxidative stress could provide new targets for both
preventive and therapeutic interventions in the treatment of chronic inflammation or any …

Dendritic cells (DCs) play crucial roles in the pathogenesis of rheumatoid arthritis (RA), a
prototypic autoimmune disease characterized by chronic synovitis and joint destruction …

Angiogenesis plays a key role in the pathological process of inflammation and invasion of
the synovium, and primarily drives the progression of rheumatoid arthritis (RA). Recent …

Rheumatoid arthritis (RA) is a chronic, progressive inflammatory and systemic autoimmune
disease resulting in severe joint destruction, lifelong suffering and considerable disability …

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterised by joint pain and
swelling, synovial hyperplasia, cartilage damage, and bone destruction. The mechanisms of …

Dendritic cells (DC) are heterogeneous cell populations essential for both inducing immunity
and maintaining immune tolerance. Chronic inflammatory contexts, such as found in …