The c-Jun N-terminal kinases (JNKs), as members of the mitogen-activated protein kinase
(MAPK) family, mediate eukaryotic cell responses to a wide range of abiotic and biotic stress …

The c-Jun N-terminal kinases (JNKs), with its members JNK1, JNK2, and JNK3, is a
subfamily of (MAPK) mitogen-activated protein kinases. JNK signaling regulates a wide …

Imidacloprid (IMI) is a neonicotinoid compound widely used in agriculture production,
causing surface water pollution and threatening non-target organisms. The aim of this study …

Interruption of iron homeostasis is correlated with cell ferroptosis and degenerative
diseases. Nuclear receptor coactivator 4 (NCOA4)-mediated ferritinophagy has been …

c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (MAPK) family
members integrate signals that affect proliferation, differentiation, survival, and migration in a …

Execution of fundamental cellular functions demands regulated protein folding homeostasis.
Endoplasmic reticulum (ER) is an active organelle existing to implement this function by …

Autophagy refers to a lysosomal degradative pathway or a process of self-cannibalization.
This pathway maintains nutrients levels for vital cellular functions during periods of …

Vinca alkaloids have been approved as anticancer drugs for more than 50 years. They have
been classified as cytotoxic chemotherapy drugs that act during cellular mitosis, enabling …

The MAPK cascades are central signaling pathways that regulate a wide variety of
stimulated cellular processes, including proliferation, differentiation, apoptosis and stress …

Obesity is a major public health problem worldwide, and it is associated with an increased
risk of developing type 2 diabetes. It is now commonly accepted that chronic inflammation …