Interactions between microtubules and actin are a basic phenomenon that underlies many
fundamental processes in which dynamic cellular asymmetries need to be established and …

Drosophila melanogaster spermatids undergo dramatic morphological changes as they
differentiate from small round cells approximately 12 μm in diameter into highly polarized …

The final stage of spermatid terminal differentiation involves the removal of their bulk
cytoplasm in a process known as spermatid individualization. Here we show that apoptotic …

Long noncoding RNAs (lncRNAs), a recently discovered class of cellular RNAs, play
important roles in the regulation of many cellular developmental processes. Although …

Mutations in the unconventional myosin VI gene, Myo6, are associated with deafness and
vestibular dysfunction in the Snell's waltzer (sv) mouse. The corresponding human gene …

Myosin VI (MyoVI) is a pointed-end-directed, actin-based motor protein,, and mutations in
the gene result in disorganization of hair cell stereocilia and cause deafness in mice. MyoVI …

Spermatozoa are generated and mature within a germline syncytium. Differentiation of
haploid syncytial spermatids into single motile sperm requires the encapsulation of each …

Unconventional myosins are a superfamily of actin-based motors implicated in diverse
cellular processes. In recent years, much progress has been made in describing their …

▪ Abstract Myosin motor proteins use the energy derived from ATP hydrolysis to move cargo
along actin tracks. Myosin VI, unlike almost all other myosins, moves toward the minus end …

Actin is found at the cortex of the cell where endocytosis occurs, but does it play a role in this
essential process? Recent studies on the unconventional myosin, myosin VI, an actin-based …