Quantifying behavior to understand the brain

TD Pereira, JW Shaevitz, M Murthy - Nature neuroscience, 2020 - nature.com
Over the past years, numerous methods have emerged to automate the quantification of
animal behavior at a resolution not previously imaginable. This has opened up a new field of …

The emergence and influence of internal states

SW Flavell, N Gogolla, M Lovett-Barron, M Zelikowsky - Neuron, 2022 - cell.com
Animal behavior is shaped by a variety of" internal states"—partially hidden variables that
profoundly shape perception, cognition, and action. The neural basis of internal states, such …

Microbiota alterations in proline metabolism impact depression

J Mayneris-Perxachs, A Castells-Nobau… - Cell metabolism, 2022 - cell.com
The microbiota-gut-brain axis has emerged as a novel target in depression, a disorder with
low treatment efficacy. However, the field is dominated by underpowered studies focusing …

TRex, a fast multi-animal tracking system with markerless identification, and 2D estimation of posture and visual fields

T Walter, ID Couzin - Elife, 2021 - elifesciences.org
Automated visual tracking of animals is rapidly becoming an indispensable tool for the study
of behavior. It offers a quantitative methodology by which organisms' sensing and decision …

Fast animal pose estimation using deep neural networks

TD Pereira, DE Aldarondo, L Willmore, M Kislin… - Nature …, 2019 - nature.com
The need for automated and efficient systems for tracking full animal pose has increased
with the complexity of behavioral data and analyses. Here we introduce LEAP (LEAP …

Computational neuroethology: a call to action

SR Datta, DJ Anderson, K Branson, P Perona, A Leifer - Neuron, 2019 - cell.com
The brain is worthy of study because it is in charge of behavior. A flurry of recent technical
advances in measuring and quantifying naturalistic behaviors provide an important …

The Mouse Action Recognition System (MARS) software pipeline for automated analysis of social behaviors in mice

C Segalin, J Williams, T Karigo, M Hui, M Zelikowsky… - Elife, 2021 - elifesciences.org
The study of naturalistic social behavior requires quantification of animals' interactions. This
is generally done through manual annotation—a highly time-consuming and tedious …

Wearable full-body motion tracking of activities of daily living predicts disease trajectory in Duchenne muscular dystrophy

V Ricotti, B Kadirvelu, V Selby, R Festenstein… - Nature medicine, 2023 - nature.com
Artificial intelligence has the potential to revolutionize healthcare, yet clinical trials in
neurological diseases continue to rely on subjective, semiquantitative and motivation …

Frontiers in quantifying wildlife behavioural responses to chemical pollution

MG Bertram, JM Martin, ES McCallum… - Biological …, 2022 - Wiley Online Library
Animal behaviour is remarkably sensitive to disruption by chemical pollution, with
widespread implications for ecological and evolutionary processes in contaminated wildlife …

Anipose: A toolkit for robust markerless 3D pose estimation

P Karashchuk, KL Rupp, ES Dickinson, S Walling-Bell… - Cell reports, 2021 - cell.com
Quantifying movement is critical for understanding animal behavior. Advances in computer
vision now enable markerless tracking from 2D video, but most animals move in 3D. Here …