A high-throughput RNA sequency of peripheral blood mononuclear cells reveals on inflammatory state in women with PCOS

R Heidarzadehpilehrood, M Pirhoushiaran… - Archives of Medical …, 2025 - Elsevier
Background Polycystic ovary syndrome (PCOS) is an endocrine and reproductive condition
affecting women of reproductive age, although its expression profiles and molecular …

[HTML][HTML] Vitamin D receptor (VDR) gene polymorphisms and risk for polycystic ovary syndrome: An updated systematic review and meta-analysis

R Heidarzadehpilehrood, HA Hamid, M Pirhoushiaran - Metabolism Open, 2024 - Elsevier
Abstract Background Vitamin D receptor (VDR) gene polymorphisms have been implicated
in polycystic ovary syndrome (PCOS). Despite VDR gene polymorphisms importance and …

[HTML][HTML] Biomarker potential of competing endogenous RNA networks in Polycystic Ovary Syndrome (PCOS)

R Heidarzadehpilehrood… - Non-coding RNA …, 2024 - ncbi.nlm.nih.gov
Polycystic ovary syndrome (PCOS) is the most common condition affecting women of
reproductive age globally. PCOS continues to be the largest contributing factor to female …

CAPN2 correlates with insulin resistance states in PCOS as evidenced by multi-dataset analysis

X Luo, Y Dong, H Zheng, X Zhou, L Rong, X Liu… - Journal of Ovarian …, 2024 - Springer
Objective IR emerges as a feature in the pathophysiology of PCOS, precipitating ovulatory
anomalies and endometrial dysfunctions that contribute to the infertility challenges …

Upregulated PCAT-1 predicts poor prognosis and reduced immune cell infiltration in head and neck squamous cell carcinoma through the miR-145-5p/FSCN-1 axis

M Pirhoushiaran, R Heidarzadehpilehrood… - Molecular Biology …, 2025 - Springer
Background LncRNA PCAT-1 is known to promote cancer proliferation, invasion, and
metastasis. However, its significance in HNSCC is not fully understood. This research …

[HTML][HTML] Polycystic Ovary Syndrome and Ferroptosis: Following Ariadne's Thread

S Geronikolou, A Pavlopoulou, I Koutelekos… - Biomedicines, 2024 - mdpi.com
Background: Recent literature suggests that ferroptosis (FPT) may be a key player in
polycystic ovary syndrome (PCOS) pathogenesis, but the underlying mechanism (s) remain …

[HTML][HTML] Dysregulated key long non-coding RNAs TP53TG1, RFPL1S, DLEU1, and HCG4 associated with epithelial-mesenchymal transition (EMT) in castration …

T Mehrabi, R Heidarzadehpilehrood… - Advances in Cancer …, 2025 - Elsevier
Background Castration-resistant prostate cancer (CRPC) is the severe and metastatic form
of prostate cancer and demands effective, reliable diagnostic and therapeutic approaches. It …

Upregulated long non-coding RNAs TMPO-AS1, DDX11-AS1, and POLE gene expression predict poor prognosis in head and neck squamous cell carcinoma …

M Mokhtarinejad, M Pirhoushiaran… - Gene Reports, 2024 - Elsevier
Background Head and neck squamous cell carcinoma (HNSCC) is prevalent and highly
aggressive. HNSCC pathogenesis is characterized by the presence of long non-coding …

Whole transcriptome analysis and construction of gene regulatory networks of granulosa cells from patients with polycystic ovary syndrome (PCOS)

Y Yuan, Q Zhang, C Du - European Journal of Medical Research, 2025 - Springer
Polycystic ovary syndrome (PCOS) is a reproductive endocrine disease characterized by
reproductive dysfunction and metabolic abnormalities. The purpose of this study was to …