[HTML][HTML] Deciphering roles of TRIMs as promising targets in hepatocellular carcinoma: current advances and future directions
J Zhang, Y Zhou, J Feng, X Xu, J Wu, C Guo - Biomedicine & …, 2023 - Elsevier
Tripartite motif (TRIM) family is assigned to RING-finger-containing ligases harboring the
largest number of proteins in E3 ubiquitin ligating enzymes. E3 ubiquitin ligases target the …
largest number of proteins in E3 ubiquitin ligating enzymes. E3 ubiquitin ligases target the …
TRIM28 Fosters Microglia Ferroptosis via Autophagy Modulation to Enhance Neuropathic Pain and Neuroinflammation
J Tang, Q Chen, L Xiang, T Tu, Y Zhang, C Ou - Molecular Neurobiology, 2024 - Springer
This study explores the molecular underpinnings of neuropathic pain (NPP) and
neuroinflammation, focusing on the role of TRIM28 in the regulation of autophagy and …
neuroinflammation, focusing on the role of TRIM28 in the regulation of autophagy and …
Identification of AKR1B10 as a key gene in primary biliary cholangitis by integrated bioinformatics analysis and experimental validation
H Wang, J Zhang, J Liu, Y Jiang, L Fu… - Frontiers in Molecular …, 2023 - frontiersin.org
Background: Primary biliary cholangitis (PBC) is a chronic autoimmune liver disease that
eventually progresses to cirrhosis and hepatocellular carcinoma (HCC) in the absence of …
eventually progresses to cirrhosis and hepatocellular carcinoma (HCC) in the absence of …
Overexpression of TRIM28 predicts an unfavorable prognosis and promotes the proliferation and migration of hepatocellular carcinoma
Y Chen, J Pang, W Liao, W Wan, T Kang, X Gan, P Lin… - Oncologie, 2023 - degruyter.com
Objectives Previous studies have shown that tripartite motif-containing 28 (TRIM28) might be
a latent target for cancer therapy. However, the detailed roles and mechanisms of TRIM28 in …
a latent target for cancer therapy. However, the detailed roles and mechanisms of TRIM28 in …