Mapping the multiscale structure of biological systems

LV Schaffer, T Ideker - Cell systems, 2021 - cell.com
Biological systems are by nature multiscale, consisting of subsystems that factor into
progressively smaller units in a deeply hierarchical structure. At any level of the hierarchy …

[HTML][HTML] LocFuse: human protein–protein interaction prediction via classifier fusion using protein localization information

J Zahiri, M Mohammad-Noori, R Ebrahimpour… - Genomics, 2014 - Elsevier
Protein–protein interaction (PPI) detection is one of the central goals of functional genomics
and systems biology. Knowledge about the nature of PPIs can help fill the widening gap …

Revealing and avoiding bias in semantic similarity scores for protein pairs

J Wang, X Zhou, J Zhu, C Zhou, Z Guo - BMC bioinformatics, 2010 - Springer
Background Semantic similarity scores for protein pairs are widely applied in functional
genomic researches for finding functional clusters of proteins, predicting protein functions …

[HTML][HTML] CellMap visualizes protein-protein interactions and subcellular localization

C Dallago, T Goldberg, MA Andrade-Navarro… - …, 2018 - pmc.ncbi.nlm.nih.gov
Many tools visualize protein-protein interaction (PPI) networks. The tool introduced here,
CellMap, adds one crucial novelty by visualizing PPI networks in the context of subcellular …

Co-expression and co-localization of hub proteins and their partners are encoded in protein sequence

A Feiglin, S Ashkenazi, A Schlessinger, B Rost… - Molecular …, 2014 - pubs.rsc.org
Spatiotemporal coordination is a critical factor in biological processes. Some hubs in protein–
protein interaction networks tend to be co-expressed and co-localized with their partners …

[图书][B] Computational prediction of physical protein-protein interactions with novel microarray analysis and efficient data integration

TT Soong - 2009 - search.proquest.com
Networks of protein-protein interactions (PPIs) provide a framework for understanding
biological processes and can give insights into the mechanisms of diseases. As …

[PDF][PDF] localization [version 1; referees: awaiting peer review]

C Dallago, T Goldberg, MA Andrade-Navarro… - pdfs.semanticscholar.org
Many tools visualize protein-protein interaction (PPI) networks. The tool introduced here,
CellMap, adds one crucial novelty by visualizing PPI networks in the context of subcellular …

Sequence-based prediction of protein-protein interactions

T Hamp - 2014 - mediatum.ub.tum.de
Understanding life on the molecular level requires knowledge about protein-protein
interactions (PPIs), but experimental data is limited and complex, rendering computational …

Interaction Variability of Human Protein Isoforms Identified through Biomedical Literature Mining

Ş Kafkas - 2012 - i-rep.emu.edu.tr
Over the last decade, advances achieved in genomic technologies have led to uncover vast
amount of protein-protein interaction data. Nevertheless, the existing proteinprotein …

[PDF][PDF] Integrated functional analysis of biological networks

D Beisser - 2011 - opus.bibliothek.uni-wuerzburg.de
In recent years high-throughput experiments provided a vast amount of data from all areas of
molecular biology, including genomics, transcriptomics, proteomics and metabolomics. Its …