Most patients diagnosed with head and neck squamous cell carcinoma (HNSCC) will
present with locally advanced disease, requiring multimodality therapy. While this approach …

The most common cancer caused by human papillomavirus (HPV) infection in the United
States is oropharyngeal cancer (OPC), and its incidence has been rising since the turn of the …

Squamous cell carcinoma of the head and neck (SCCHN) arises from epithelial cells and
occurs in the oral cavity, pharynx and larynx. Nasopharyngeal carcinoma (NPC) is a disease …

Abstract Background and purpose The Meta-Analysis of Chemotherapy in squamous cell
Head and Neck Cancer (MACH-NC) demonstrated that concomitant chemotherapy (CT) …

Neoadjuvant immunotherapy has the potential to enhance clinical outcomes by increasing
anti-tumor immune responses in the presence of abundant tumor-derived antigen in an …

Simple Summary Even with recent advances, there are urgent needs for novel therapies to
improve overall survival and decrease toxicities in the management of head and neck …

Oral squamous cell carcinoma (OSCC) is a kind of malignant tumors with low survival rate
and prone to have early metastasis and recurrence. Cisplatin is an alkylating agent which …

Head and neck cancers (HNC) are defined as malignant tumours located in the upper
aerodigestive tract and represents 5% of oncologic cases in adults in Spain. More than 90 …

Background Platinum-based chemoradiation (CCRT) is the standard treatment for Locally
Advanced Head and Neck Squamous-Cell Carcinoma (LAHNSCC). Cetuximab/RT …

Purpose To compare survival, tumor control, toxicities, and quality of life of patients with
locally advanced nasopharyngeal carcinoma (NPC) treated with induction chemotherapy …