Global prevalence and case fatality rate of Enterovirus D68 infections, a systematic review and meta-analysis

A Fall, S Kenmoe, JT Ebogo-Belobo… - PLoS Neglected …, 2022 - journals.plos.org
A substantial amount of epidemiological data has been reported on Enterovirus D68 (EV-
D68) infections after the 2014 outbreak. Our goal was to map the case fatality rate (CFR) and …

The Picornaviridae Family: Knowledge Gaps, Animal Models, Countermeasures, and Prototype Pathogens

R Andino, K Kirkegaard, A Macadam… - The Journal of …, 2023 - academic.oup.com
Picornaviruses are nonenveloped particles with a single-stranded RNA genome of positive
polarity. This virus family includes poliovirus, hepatitis A virus, rhinoviruses, and …

Epidemiological dynamics of enterovirus D68 in the United States and implications for acute flaccid myelitis

SW Park, M Pons-Salort, K Messacar, C Cook… - Science Translational …, 2021 - science.org
Acute flaccid myelitis (AFM) recently emerged in the United States as a rare but serious
neurological condition since 2012. Enterovirus D68 (EV-D68) is thought to be a main …

European non-polio enterovirus network: introduction of hospital-based surveillance network to understand the true disease burden of non-polio enterovirus and …

H Harvala, KSM Benschop, N Berginc, S Midgley… - Microorganisms, 2021 - mdpi.com
Background. Non-polio enteroviruses (EVs) and human parechoviruses (PeVs) cause a
wide range of human infections. Limited data on their true disease burden exist as …

Animal models of enterovirus D68 infection and disease

MS Vermillion, J Dearing, Y Zhang, DR Adney… - Journal of …, 2022 - Am Soc Microbiol
ABSTRACT Human enterovirus D68 (EV-D68) is a globally reemerging respiratory
pathogen that is associated with the development of acute flaccid myelitis (AFM) in children …

Cross-reactive antibody responses against nonpoliovirus enteroviruses

AB Rosenfeld, EQL Shen, M Melendez, N Mishra… - MBio, 2022 - Am Soc Microbiol
Enteroviruses are among the most common human viral pathogens. Infection with members
of a subgroup of viruses within this genus, the nonpoliovirus enteroviruses (NPEVs), can …

Evolution, geographic spreading, and demographic distribution of Enterovirus D68

EB Hodcroft, R Dyrdak, C Andrés, A Egli, J Reist… - PLoS …, 2022 - journals.plos.org
Worldwide outbreaks of enterovirus D68 (EV-D68) in 2014 and 2016 have caused serious
respiratory and neurological disease. We collected samples from several European …

Neutralizing activity of intravenous immune globulin products against enterovirus D68 strains isolated in Japan

K Yoshida, M Muramatsu, H Shimizu - BMC Infectious Diseases, 2023 - Springer
Abstract Background Enterovirus D68 (EV-D68), belonging to Enterovirus D, is a unique
human enterovirus mainly associated with common respiratory diseases. However, EV-D68 …

Enterovirus D68 seroepidemiology in Taiwan, a cross sectional study from 2017

JT Lee, WL Shih, TY Yen, AL Cheng, CY Lu… - PLoS …, 2020 - journals.plos.org
Background Enterovirus D68 (EV-D68) was discovered in 1962 and has unique
characteristics compared to the characteristics of other enteroviruses. There were few …

Enhanced Enterovirus D68 replication in neuroblastoma cells is associated with a cell culture-adaptive amino acid substitution in VP1

S Sooksawasdi Na Ayudhya, A Meijer, L Bauer… - Msphere, 2020 - Am Soc Microbiol
Since its emergence in the United States in 2014, enterovirus D68 (EV-D68) has been and
is associated with severe respiratory diseases and acute flaccid myelitis. Even though EV …