The potential role of gap junctional plasticity in the regulation of state
P Coulon, CE Landisman - Neuron, 2017 - cell.com
Electrical synapses are the functional correlate of gap junctions and allow transmission of
small molecules and electrical current between coupled neurons. Instead of static pores …
small molecules and electrical current between coupled neurons. Instead of static pores …
Synaptic protein interaction networks encode experience by assuming stimulus-specific and brain-region-specific states
JD Lautz, KB Tsegay, Z Zhu, EP Gniffke, JP Welsh… - Cell reports, 2021 - cell.com
A core network of widely expressed proteins within the glutamatergic post-synapse mediates
activity-dependent synaptic plasticity throughout the brain, but the specific proteomic …
activity-dependent synaptic plasticity throughout the brain, but the specific proteomic …
Relationship of Impairments in Associative Learning With Intellectual Disability and Cerebellar Hypoplasia in Autistic Children
JP Welsh, J Munson, T St John, CN Meehan… - Neurology, 2023 - AAN Enterprises
Background and Objectives The severity of autism spectrum disorder (ASD) varies widely
and is associated with intellectual disability (ID) and brain dysmorphology. We tested the …
and is associated with intellectual disability (ID) and brain dysmorphology. We tested the …
The role of electrical coupling in rhythm generation in small networks
Generation of rhythmic activity in numerous systems has been shown to depend on
electrical coupling. Small networks provide a strong advantage for studying electrical …
electrical coupling. Small networks provide a strong advantage for studying electrical …
Shank3 mutations impair electrical synapse scaffolding and transmission in mouse brain
J Lautz, Z Zhu, HE Speed, SEP Smith, JP Welsh - bioRxiv, 2021 - biorxiv.org
Shank3 mutations contribute to intellectual disability. Because SHANK3 is a protein scaffold
that helps organize the multiprotein network of the glutamatergic postsynaptic density (PSD) …
that helps organize the multiprotein network of the glutamatergic postsynaptic density (PSD) …