Exosomes are well-known key mediators of intercellular communication and contribute to
various physiological and pathological processes. Their biogenesis involves four key steps …

Exosomes are a subtype of membrane-contained vesicles 40–200 nm in diameter that are
secreted by cells into their surroundings. By transporting proteins, lipids, mRNA, miRNA …

Extracellular vesicles (EVs) are naturally released membrane vesicles that act as carriers of
proteins and RNAs for intercellular communication. With various biomolecules and specific …

Abstract Background Circular RNAs (circRNAs) have important regulatory functions in
cancer, but the role of circRNAs in the tumor microenvironment (TME) remains unclear …

Exosomes are membrane extracellular vesicles secreted by almost all kinds of cells, which
are rich in proteins, lipids, and nucleic acids. As a medium of intercellular communication …

Abstract PD-L1+ tumor-derived extracellular vesicles (TEVs) cause systemic
immunosuppression and possibly resistance to anti-PD-L1 antibody (αPD-L1) blockade …

The current diagnosis and treatment of sarcoma continue to show limited timeliness and
efficacy. In order to enable the early detection and management of sarcoma, increasing …

NEDD8 (Neural precursor cell expressed developmentally downregulated protein 8) is an
ubiquitin-like protein that is covalently attached to a lysine residue of a protein substrate …

Simple Summary Exosomes are nanometer-sized vesicles released by different cells that
are important in the normal functioning of the body. In cancer, exosomes have been found to …

Background Exosomes are small vesicles released by cells, which have crucial functions in
intercellular communication. Exosomes originated from cell membrane invagination and are …