Diversification of type VI secretion system toxins reveals ancient antagonism among bee gut microbes

MI Steele, WK Kwong, M Whiteley, NA Moran - MBio, 2017 - Am Soc Microbiol
Microbial communities are shaped by interactions among their constituent members. Some
Gram-negative bacteria employ type VI secretion systems (T6SSs) to inject protein toxins …

Genotypic and phenotypic diversity of Staphylococcus aureus isolates from cystic fibrosis patient lung infections and their interactions with Pseudomonas aeruginosa

EE Bernardy, RA Petit III, V Raghuram, AM Alexander… - MBio, 2020 - Am Soc Microbiol
Staphylococcus aureus has recently overtaken Pseudomonas aeruginosa as the most
commonly recognized bacterial pathogen that infects the respiratory tracts of individuals with …

VxrB influences antagonism within biofilms by controlling competition through extracellular matrix production and type 6 secretion

JK Teschler, E Jiménez-Siebert, H Jeckel, PK Singh… - MBio, 2022 - Am Soc Microbiol
The human pathogen Vibrio cholerae grows as biofilms, communities of cells encased in an
extracellular matrix. When growing in biofilms, cells compete for resources and space. One …

Horizontal gene transfer of functional type VI killing genes by natural transformation

J Thomas, SS Watve, WC Ratcliff, BK Hammer - MBio, 2017 - Am Soc Microbiol
Horizontal gene transfer (HGT) can have profound effects on bacterial evolution by allowing
individuals to rapidly acquire adaptive traits that shape their strategies for competition. One …

Diversification of the type VI secretion system in Agrobacteria

CF Wu, AJ Weisberg, EW Davis, L Chou, S Khan… - MBio, 2021 - Am Soc Microbiol
The type VI secretion system (T6SS) is used by many Gram-negative bacteria to deploy toxic
effectors for interbacterial competition. This system provides a competitive advantage in …

Anomalous diffusion of nanoparticles in the spatially heterogeneous biofilm environment

B Coppens, TER Belpaire, J Pešek, HP Steenackers… - iScience, 2023 - cell.com
Biofilms contain extracellular polymeric substances (EPS) that provide structural support and
restrict penetration of antimicrobial treatment. To overcome limited penetration …

Plant-Pathogenic Agrobacterium tumefaciens Strains Have Diverse Type VI Effector-Immunity Pairs and Vary in In-Planta Competitiveness

CF Wu, MNM Santos, ST Cho… - Molecular Plant …, 2019 - Am Phytopath Society
The type VI secretion system (T6SS) is used by gram-negative bacteria to translocate
effectors that can antagonize other bacterial cells. Models predict the variation in collections …

Evolution of interbacterial antagonism in bee gut microbiota reflects host and symbiont diversification

MI Steele, NA Moran - Msystems, 2021 - Am Soc Microbiol
Gram-negative bacteria frequently possess type VI secretion systems (T6SSs), protein
complexes that are able to inject toxic proteins into nearby cells. Many aspects of T6SS …

Fitness and Productivity Increase with Ecotypic Diversity among Escherichia coli Strains That Coevolved in a Simple, Constant Environment

DD Yang, A Alexander, M Kinnersley… - Applied and …, 2020 - Am Soc Microbiol
The productivity of a biological community often correlates with its diversity. In the microbial
world this phenomenon can sometimes be explained by positive, density-dependent …

Type IV pilus shapes a 'bubble-burst'pattern opposing spatial intermixing of two interacting bacterial populations

M Wang, X Chen, Y Ma, YQ Tang… - Microbiology …, 2022 - Am Soc Microbiol
Microbes are social organisms that commonly live in sessile biofilms. Spatial patterns of
populations within biofilms can be important determinants of community-level properties …