Critical illness due to infection in people living with HIV

GA Richards, J Zamparini, I Kalla, A Laher… - The Lancet …, 2024 - thelancet.com
People living with HIV comprise a substantial number of the patients admitted to intensive
care. This number varies according to geography, but all areas of the world are affected. In …

Development and Validation of a UPLC-MS/MS Method for Therapeutic Drug Monitoring, Pharmacokinetic and Stability Studies of First-Line Antituberculosis Drugs in …

M Abouzid, K Kosicka-Noworzyń… - Molecules, 2024 - mdpi.com
Tuberculosis (TB) remains one of the leading global causes of mortality. Several methods
have been established to detect anti-TB agents in human plasma and serum. However …

Isoniazid and rifampicin exposure during treatment in drug-susceptible TB

OW Akkerman, RDC Dijkwel… - … of Tuberculosis and …, 2023 - ingentaconnect.com
BACKGROUND: Observational real-world studies on therapeutic drug monitoring (TDM) in
relation to pharmacokinetic (PK) target values are lacking. This study aims to describe the …

Dried Blood Spot Sampling to Assess Rifampicin Exposure and Treatment Outcomes among Native and Non-Native Tuberculosis Patients in Paraguay: An …

S Ghimire, G Molinas, A Battaglia, N Martinez… - Pharmaceutics, 2023 - mdpi.com
The aim of this study was to evaluate the difference in drug exposure of rifampicin in native
versus non-native Paraguayan populations using dried blood spots (DBS) samples …

USE OF HIGH DOSE RIFAMPICIN FOR THE TREATMENT OF TUBERCULOSIS MENINGITIS PATIENTS: A SYSTEMATIC REVIEW

ARA Hidayat, FS Zulkarnain, MIP Agusti - Journal of Advanced …, 2023 - jarmhs.com
Aim: The objective of this study is to summarize and evaluate the use of high-dose rifampicin
for the treatment of tuberculosis meningitis. Methods: A systematic search strategy was …