The perception that intracellular lipolysis is a straightforward process that releases fatty
acids from fat stores in adipose tissue to generate energy has experienced major revisions …

Epidermal barrier integrity could be influenced by various factors involved in epidermal cell
differentiation and proliferation, cell–cell adhesion, and skin lipids. Dysfunction of this barrier …

The corneocyte lipid envelope, composed of covalently bound ceramides and fatty acids, is
important to the integrity of the permeability barrier in the stratum corneum, and its absence …

The primary purpose of the epidermis of terrestrial vertebrates is to produce the stratum
corneum, which serves as the interface between the organism and the environment. As …

The epidermis-specific lipid acylceramide plays a pivotal role in the formation of the
permeability barrier in the skin; abrogation of its synthesis causes the skin disorder …

The human genome encodes nine enzymes belonging to the patatin-like phospholipase
domain-containing lipase (PNPLA)/Ca 2+-independent phospholipase A 2 (iPLA 2) family …

The α/β-Hydrolase domain-containing protein 5 (ABHD5; also known as comparative gene
identification-58, or CGI-58) is the causative gene of the Chanarin-Dorfman syndrome …

The skin is a flexible organ that forms a barrier between the environment and the body's
interior; it is involved in the immune response, in protection and regulation, and is a dynamic …

Mutations in the genes coding for patatin-like phospholipase domain-containing 1 (PNPLA1)
and α/β-hydrolase domain-containing 5 (ABHD5), also known as comparative gene …

The skin permeability barrier is indispensable for maintaining water inside the body and
preventing the invasion of pathogens and allergens; abnormalities lead to skin disorders …