MicroRNAs (miRNAs) are small non-coding RNAs that function as guide molecules in RNA
silencing. Targeting most protein-coding transcripts, miRNAs are involved in nearly all …

RNA interference (RNAi) is a natural process through which expression of a targeted gene
can be knocked down with high specificity and selectivity. Using available technology and …

MicroRNAs are RNAs of about 18–24 nucleotides in lengths, which are found in the small
noncoding RNA class and have a crucial role in the posttranscriptional regulation of gene …

MicroRNAs (miRNAs) regulate expression of their target mRNAs through the RNA-induced
silencing complex (RISC), which contains an Argonaute (Ago) family protein as a core …

In contrast to microRNAs and Piwi-associated RNAs, short interfering RNAs (siRNAs) are
seemingly dispensable for host-directed gene regulation in Drosophila. This notion is based …

Until recently, only nematodes among animals had a well-defined endogenous small
interfering RNA (endo-siRNA) pathway. This has changed dramatically with the recent …

Influenza A virus (IAV) causes annual epidemics and occasional pandemics, and is one of
the best-characterized human RNA viral pathogens 1. However, a physiologically relevant …

In Arabidopsis thaliana (Arabidopsis), DICER-LIKE1 (DCL1) functions together with the
double-stranded RNA binding protein (dsRBP), DRB1, to process microRNAs (miRNAs) …

MicroRNAs play central roles in controlling gene expression in human cells. Sequencing
data show that many miRNAs are produced at different levels and as multiple isoforms that …

The discovery of RNA interference (RNAi) is among the most significant biomedical
breakthroughs in recent history. Multiple classes of small RNA, including small-interfering …