Multipotential and systemic effects of traumatic brain injury

N Sabet, Z Soltani, M Khaksari - Journal of neuroimmunology, 2021 - Elsevier
Traumatic brain injury (TBI) is one of the leading causes of disability and mortality of people
at all ages. Biochemical, cellular and physiological events that occur during primary injury …

[HTML][HTML] Nicotinamide as a foundation for treating neurodegenerative disease and metabolic disorders

K Maiese - Current neurovascular research, 2021 - ncbi.nlm.nih.gov
Neurodegenerative disorders impact more than one billion individuals worldwide and are
intimately tied to metabolic disease that can affect another nine hundred individuals …

Exosomes derived from bone marrow mesenchymal stem cells attenuate neurological damage in traumatic brain injury by alleviating glutamate-mediated …

Z Zhuang, M Liu, J Luo, X Zhang, Z Dai, B Zhang… - Experimental …, 2022 - Elsevier
Background Traumatic brain injury (TBI) is one of the major contributors to disability and
death worldwide. Glutamate-mediated excitotoxicity, one of the secondary injuries occurring …

[HTML][HTML] Human umbilical cord mesenchymal stem cell-derived exosomes promote neurological function recovery in rat after traumatic brain injury by inhibiting the …

L Cui, W Luo, W Jiang, H Li, J Xu, X Liu, B Wang… - Regenerative …, 2022 - Elsevier
Traumatic brain injury (TBI) is a serious neurological disorder with increasing worldwide
incidence. Emerging evidence has shown a significant therapeutic role of mesenchymal …

Mesenchymal stem cells protect against TBI-induced pyroptosis in vivo and in vitro through TSG-6

Z Feng, S Hua, W Li, J Han, F Li, H Chen… - Cell Communication and …, 2022 - Springer
Background Pyroptosis, especially microglial pyroptosis, may play an important role in
central nervous system pathologies, including traumatic brain injury (TBI). Transplantation of …

The impact of aging and oxidative stress in metabolic and nervous system disorders: programmed cell death and molecular signal transduction crosstalk

K Maiese - Frontiers in immunology, 2023 - frontiersin.org
Life expectancy is increasing throughout the world and coincides with a rise in non-
communicable diseases (NCDs), especially for metabolic disease that includes diabetes …

Mesenchymal stem cell therapy: a potential treatment targeting pathological manifestations of traumatic brain injury

K Zhang, Y Jiang, B Wang, T Li… - … Medicine and Cellular …, 2022 - Wiley Online Library
Traumatic brain injury (TBI) makes up a large proportion of acute brain injuries and is a
major cause of disability globally. Its complicated etiology and pathogenesis mainly include …

The evolving role of extracellular vesicles (exosomes) as biomarkers in traumatic brain injury: Clinical perspectives and therapeutic implications

NA Khan, M Asim, A El-Menyar, KH Biswas… - Frontiers in Aging …, 2022 - frontiersin.org
Developing effective disease-modifying therapies for neurodegenerative diseases (NDs)
requires reliable diagnostic, disease activity, and progression indicators. While desirable …

Cornerstone Cellular pathways for metabolic disorders and Diabetes Mellitus: non-coding RNAs, wnt signaling, and AMPK

K Maiese - Cells, 2023 - mdpi.com
Metabolic disorders and diabetes (DM) impact more than five hundred million individuals
throughout the world and are insidious in onset, chronic in nature, and yield significant …

Microglia: Formidable Players in Alzheimer's Disease and Other Neurodegenerative Disorders

K Maiese - Current Neurovascular Research, 2023 - ingentaconnect.com
Microglia account for approximately fifteen percent of the cell population in the brain and
spinal cord. These cells, considered to be family members of glial cells, have an active role …