Ventilation is inherently a dynamic process. The present-day clinical practice of
concentrating on the static inflation characteristics of the individual tidal cycle (plateau …

The adverse effects of mechanical ventilation in acute respiratory distress syndrome (ARDS)
arise from two main causes: unphysiological increases of transpulmonary pressure and …

Purpose We hypothesized that the ventilator-related causes of lung injury may be unified in
a single variable: the mechanical power. We assessed whether the mechanical power …

Several factors have been recognized as possible triggers of ventilator-induced lung injury
(VILI). The first is pressure (thus the 'barotrauma'), then the volume (hence the 'volutrauma') …

Background Mechanical power (MP) is the energy delivered to the respiratory system over
time during mechanical ventilation. Our aim was to compare the currently available methods …

Acute respiratory distress syndrome is a multifactorial lung injury that continues to be
associated with high levels of morbidity and mortality. Mechanical ventilation, although …

Background Lung-protective ventilation strategy suggests the use of low tidal volume,
depending on ideal body weight, and adequate levels of PEEP. However, reducing tidal …

Background Mechanical power is a summary variable including all the components which
can possibly cause VILI (pressures, volume, flow, respiratory rate). Since the complexity of …

Advanced respiratory monitoring involves several mini-or noninvasive tools, applicable at
bedside, focused on assessing lung aeration and morphology, lung recruitment and …

It has been shown that mechanical ventilation in patients with, or at high-risk for, the
development of acute respiratory distress syndrome (ARDS) can be a double-edged sword …