Control mechanisms that regulate body size and tissue size have been sought at both the
cellular and organismal level. Cell-level studies have revealed much about the control of cell …

A quarter of a century has passed since bombyxin, the first insulin-like peptide identified in
insects, was discovered in the silkmoth Bombyx mori. During these years, bombyxin has …

The mechanisms that control the growth rate of internal tissues during postembryonic
development are poorly understood. In insects, the growth rate of imaginal disks varies with …

The developmental mechanisms that control body size and the relative sizes of body parts
are today best understood in insects. Size is controlled by the mechanisms that cause …

Insulin is a molecule that has played a key role in several of the most important landmarks in
medical and biological research. It is one of the most extensively studied protein hormones …

The effects of starvation and feeding on the release of bombyxin, a peptide of insulin
superfamily in insects, from the larval brain of the silkworm Bombyx mori were investigated …

Bombyxin is a 5 kDa secretory brain peptide that belongs to the insulin family. Bombyxin of
the silkmoth Bombyx mori can induce adult development when injected into brain-removed …

In the pond snail Lymnaea stagnalis, the growth regulating system consists of (1) about 200
neuroendocrine light green cells, located in four clusters in the cerebral ganglia, and (2) the …

Monoclonal antibodies were raised against pure, native bombyxin‐II (bombyxin‐II antibody)
and against a synthetic nonapeptide corresponding to the amino‐terminus of the C‐peptide …

In vertebrates, insulin-like growth factors (IGFs) play important roles in the regulation of
growth and development. Although the principal source of circulating IGFs is the liver, IGFs …