Parkinson's disease, aging and adult neurogenesis: Wnt/β‐catenin signalling as the key to unlock the mystery of endogenous brain repair

B Marchetti, C Tirolo, F L'Episcopo, S Caniglia… - Aging cell, 2020 - Wiley Online Library
A common hallmark of age‐dependent neurodegenerative diseases is an impairment of
adult neurogenesis. Wingless‐type mouse mammary tumor virus integration site (Wnt)/β …

Pathogenetic pathways of cognitive dysfunction and dementia in metabolic syndrome

YY Borshchev, YP Uspensky, MM Galagudza - Life sciences, 2019 - Elsevier
The prevalence of dementia worldwide is growing at an alarming rate. A number of studies
and meta-analyses have provided evidence for increased risk of dementia in patients with …

Three-dimensional morphometric analysis reveals time-dependent structural changes in microglia and astrocytes in the central amygdala and hypothalamic …

F Althammer, HC Ferreira-Neto, M Rubaharan… - Journal of …, 2020 - Springer
Background Cardiovascular diseases, including heart failure, are the most common cause of
death globally. Recent studies support a high degree of comorbidity between heart failure …

Heart rate variability in patients with dementia or neurocognitive disorders: A systematic review and meta-analysis

YC Cheng, YC Huang… - Australian & New Zealand …, 2022 - journals.sagepub.com
Objective: Heart rate variability, a quantitative measure of mainly parasympathetic activity,
has been applied in evaluating many types of psychiatric and neurological disorders …

Cognitive impairment in myocardial infarction and heart failure

K Jinawong, N Apaijai, N Chattipakorn… - Acta …, 2021 - Wiley Online Library
Myocardial infarction (MI) occurs when coronary blood flow is decreased due to an
obstruction/occlusion of the vessels, leading to myocardial death and progression to heart …

Cognitive impairment in heart failure: landscape, challenges, and future directions

M Yang, D Sun, Y Wang, M Yan, J Zheng… - Frontiers in …, 2022 - frontiersin.org
Heart failure (HF) is a major global healthcare problem accounting for substantial
deterioration of prognosis. As a complex clinical syndrome, HF often coexists with multi …

Angiotensin II–mediated neuroinflammation in the hippocampus contributes to neuronal deficits and cognitive impairment in heart failure rats

F Althammer, RK Roy, MK Kirchner, E Campos-Lira… - …, 2023 - Am Heart Assoc
Background: Heart failure (HF) is a debilitating disease affecting> 64 million people
worldwide. In addition to impaired cardiovascular performance and associated systemic …

Cognitive dysfunction in heart failure: pathophysiology and implications for patient management

S Ye, Q Huynh, EL Potter - Current Heart Failure Reports, 2022 - Springer
Abstract Purpose of Review There is increasing recognition of the prevalence and impact of
cognitive dysfunction (CD) in heart failure (HF) patients. This contemporary review appraises …

Cognitive impairment in patients with heart failure: Molecular mechanism and therapy

Y Wu, L Chen, F Zhong, K Zhou, C Lu, X Cheng… - Heart Failure …, 2023 - Springer
Heart failure (HF) is associated with multiple organ dysfunction and many comorbidities. Its
incidence is high among the elderly and is a major health burden worldwide. Cognitive …

Heart–brain interaction in cardiogenic dementia: pathophysiology and therapeutic potential

J Liu, G Xiao, Y Liang, S He, M Lyu… - Frontiers in Cardiovascular …, 2024 - frontiersin.org
Diagnosis and treatment of patients with cardiovascular and neurologic diseases primarily
focus on the heart and brain, respectively. An increasing number of preclinical and clinical …