Recent advances in systems and synthetic biology approaches for developing novel cell-factories in non-conventional yeasts
Microbial bioproduction of chemicals, proteins, and primary metabolites from cheap carbon
sources is currently an advancing area in industrial research. The model yeast …
sources is currently an advancing area in industrial research. The model yeast …
[HTML][HTML] Metabolic engineering of the shikimate pathway for production of aromatics and derived compounds—present and future strain construction strategies
NJH Averesch, JO Krömer - Frontiers in Bioengineering and …, 2018 - frontiersin.org
The aromatic nature of shikimate pathway intermediates gives rise to a wealth of potential
bio-replacements for commonly fossil fuel-derived aromatics, as well as naturally produced …
bio-replacements for commonly fossil fuel-derived aromatics, as well as naturally produced …
[HTML][HTML] Rewiring carbon metabolism in yeast for high level production of aromatic chemicals
The production of bioactive plant compounds using microbial hosts is considered a safe,
cost-competitive and scalable approach to their production. However, microbial production …
cost-competitive and scalable approach to their production. However, microbial production …
Engineering plant secondary metabolism in microbial systems
Engineering Plant Secondary Metabolism in Microbial Systems | Plant Physiology | Oxford
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Systems engineering of Escherichia coli for high-level shikimate production
To further increase the production efficiency of microbial shikimate, a valuable compound
widely used in the pharmaceutical and chemical industries, ten key target genes contributing …
widely used in the pharmaceutical and chemical industries, ten key target genes contributing …
Building microbial factories for the production of aromatic amino acid pathway derivatives: from commodity chemicals to plant-sourced natural products
The aromatic amino acid biosynthesis pathway, together with its downstream branches,
represents one of the most commercially valuable biosynthetic pathways, producing a …
represents one of the most commercially valuable biosynthetic pathways, producing a …
[HTML][HTML] Xylose and shikimate transporters facilitates microbial consortium as a chassis for benzylisoquinoline alkaloid production
Plant-sourced aromatic amino acid (AAA) derivatives are a vast group of compounds with
broad applications. Here, we present the development of a yeast consortium for efficient …
broad applications. Here, we present the development of a yeast consortium for efficient …
A repackaged CRISPR platform increases homology-directed repair for yeast engineering
Inefficient homology-directed repair (HDR) constrains CRISPR–Cas9 genome editing in
organisms that preferentially employ nonhomologous end joining (NHEJ) to fix DNA double …
organisms that preferentially employ nonhomologous end joining (NHEJ) to fix DNA double …
[HTML][HTML] Host and Pathway Engineering for Enhanced Lycopene Biosynthesis in Yarrowia lipolytica
Carotenoids are a class of molecules with commercial value as food and feed additives with
nutraceutical properties. Shifting carotenoid synthesis from petrochemical-based precursors …
nutraceutical properties. Shifting carotenoid synthesis from petrochemical-based precursors …
Production of volatiles relation to bread aroma in flour-based fermentation with yeast
The aim of this study is to produce a bread aroma mixture in flour-based fermentation that
can potentially be added in bread dough forming after selection of yeast strains and …
can potentially be added in bread dough forming after selection of yeast strains and …